Explore MARCO gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0795
|
| Target Name |
MARCO
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8685
|
| Gene ID |
100052243 (Equus caballus), 101083611 (Felis catus), 17167 (Mus musculus), 367391 (Rattus norvegicus)
476117 (Canis lupus familiaris), 505632 (Bos taurus), 694432 (Macaca mulatta), 8685 (Homo sapiens)
|
| Target Alternative Names |
Ly112,MARCO,Macrophage receptor MARCO,Macrophage receptor with collagenous structure,Marco,SCARA2,SR-A6,Scara2,Scavenger receptor class A member 2
|
| Uniprot Accession |
Q60754,Q9UEW3
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Phagosome
|
| Gene Ensembl |
ENSECAG00000012151, ENSMUSG00000026390, ENSCAFG00845029094, ENSBTAG00000018473, ENSMMUG00000002610, ENSG00000019169
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of MARCO cDNA Clones/ORF Plasmid
MARCO siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8685 | Pre-made Human MARCO/SR-A6/SCARA2 siRNA oligo Duplex | 8685 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo367391 | Pre-made Rat Marco siRNA oligo Duplex | 367391 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17167 | Pre-made Mouse Marco/Ly112/Scara2 siRNA oligo Duplex | 17167 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694432 | Pre-made Cynomolgus/Rhesus macaque MARCO siRNA oligo Duplex | 694432 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083611 | Pre-made Cat/Feline MARCO siRNA oligo Duplex | 101083611 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476117 | Pre-made Dog/Canine MARCO siRNA oligo Duplex | 476117 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505632 | Pre-made Bovines/Cattle MARCO siRNA oligo Duplex | 505632 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052243 | Pre-made Equine/Horse MARCO siRNA oligo Duplex | 100052243 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MARCO antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0795-Ab | Human | Anti-Human MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0795-Ab | Rat | Anti-Rat MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0795-Ab | Mouse | Anti-Mouse MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0795-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0795-Ab | Cat/Feline | Anti-Cat/Feline MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0795-Ab | Dog/Canine | Anti-Dog/Canine MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0795-Ab | Bovines/Cattle | Anti-Bovines/Cattle MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0795-Ab | Equine/Horse | Anti-Equine/Horse MARCO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
MARCO VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0795-Ag | Human | Human MARCO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0795-Ag | Rat | Rat MARCO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0795-Ag | Mouse | Mouse MARCO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0795-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MARCO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0795-Ag | Cat/Feline | Cat/Feline MARCO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0795-Ag | Dog/Canine | Dog/Canine MARCO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0795-Ag | Bovines/Cattle | Bovines/Cattle MARCO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0795-Ag | Equine/Horse | Equine/Horse MARCO VLP (virus-like particle) | HEK293 | Products Developing |
