Explore LYPLA1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013]
| Target ID |
GM-MP0789
|
| Target Name |
LYPLA1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10434
|
| Gene ID |
100146256 (Equus caballus), 101080683 (Felis catus), 10434 (Homo sapiens), 18777 (Mus musculus) 25514 (Rattus norvegicus), 539992 (Bos taurus), 609018 (Canis lupus familiaris), 693700 (Macaca mulatta)
|
| Target Alternative Names |
25KDL,APT-1,APT1,Acyl-protein thioesterase 1,Gm39587,LPL-I,LPL1,LYPLA1,Lypla1,LysoPLA I),Lysophospholipase 1,Lysophospholipase I (LPL-I,Palmitoyl-protein hydrolase,Pla1a,hAPT1,lysoPLA
|
| Uniprot Accession |
O75608,P97823,P70470,Q3MHR0
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Choline metabolism in cancer, Glycerophospholipid metabolism
|
| Gene Ensembl |
ENSECAG00000016530, ENSG00000120992, ENSMUSG00000025903, ENSBTAG00000004243, ENSCAFG00845025526, ENSMMUG00000013157
|
Pre-made viral vector of LYPLA1 cDNA Clones/ORF Plasmid
LYPLA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10434 | Pre-made Human LYPLA1/APT1/LPL1 siRNA oligo Duplex | 10434 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25514 | Pre-made Rat Lypla1/25KDL/APT-1 siRNA oligo Duplex | 25514 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18777 | Pre-made Mouse Lypla1/APT-1/LPL-I siRNA oligo Duplex | 18777 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693700 | Pre-made Cynomolgus/Rhesus macaque LYPLA1 siRNA oligo Duplex | 693700 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080683 | Pre-made Cat/Feline LYPLA1 siRNA oligo Duplex | 101080683 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609018 | Pre-made Dog/Canine LYPLA1 siRNA oligo Duplex | 609018 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539992 | Pre-made Bovines/Cattle LYPLA1 siRNA oligo Duplex | 539992 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146256 | Pre-made Equine/Horse LYPLA1 siRNA oligo Duplex | 100146256 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LYPLA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0789-Ab | Human | Anti-Human LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0789-Ab | Rat | Anti-Rat LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0789-Ab | Mouse | Anti-Mouse LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0789-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0789-Ab | Cat/Feline | Anti-Cat/Feline LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0789-Ab | Dog/Canine | Anti-Dog/Canine LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0789-Ab | Bovines/Cattle | Anti-Bovines/Cattle LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0789-Ab | Equine/Horse | Anti-Equine/Horse LYPLA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LYPLA1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0789-Ag | Human | Human LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0789-Ag | Rat | Rat LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0789-Ag | Mouse | Mouse LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0789-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0789-Ag | Cat/Feline | Cat/Feline LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0789-Ag | Dog/Canine | Dog/Canine LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0789-Ag | Bovines/Cattle | Bovines/Cattle LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0789-Ag | Equine/Horse | Equine/Horse LYPLA1 VLP (virus-like particle) | HEK293 | Products Developing |