Explore LRRC8A/SWELL1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0767
|
| Target Name |
LRRC8A/SWELL1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
56262
|
| Gene ID |
100066843 (Equus caballus), 101082860 (Felis catus), 241296 (Mus musculus), 311846 (Rattus norvegicus)
491309 (Canis lupus familiaris), 505605 (Bos taurus), 56262 (Homo sapiens), 717074 (Macaca mulatta)
|
| Target Alternative Names |
LRRC8A,Lrrc8a,ebo,Lrrc8,SWELL1,mKIAA1437,LLRC8A,AGM5,LRRC8,HsLRRC8A
|
| Uniprot Accession |
Q80WG5,Q4V8I7,Q8IWT6
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000013359, ENSMUSG00000007476, ENSCAFG00845025448, ENSBTAG00000013030, ENSG00000136802, ENSMMUG00000017799
|
| Target Classification |
|
Pre-made viral vector of LRRC8A/SWELL1 cDNA Clones/ORF Plasmid
LRRC8A/SWELL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo56262 | Pre-made Human LRRC8A/AGM5/LRRC8 siRNA oligo Duplex | 56262 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo311846 | Pre-made Rat Lrrc8a/Lrrc8 siRNA oligo Duplex | 311846 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo241296 | Pre-made Mouse Lrrc8a/ebo/Lrrc8 siRNA oligo Duplex | 241296 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717074 | Pre-made Cynomolgus/Rhesus macaque LRRC8A siRNA oligo Duplex | 717074 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082860 | Pre-made Cat/Feline LRRC8A siRNA oligo Duplex | 101082860 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491309 | Pre-made Dog/Canine LRRC8A siRNA oligo Duplex | 491309 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505605 | Pre-made Bovines/Cattle LRRC8A/LLRC8A siRNA oligo Duplex | 505605 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066843 | Pre-made Equine/Horse LRRC8A siRNA oligo Duplex | 100066843 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LRRC8A/SWELL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0767-Ab | Human | Anti-Human LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0767-Ab | Rat | Anti-Rat LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0767-Ab | Mouse | Anti-Mouse LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0767-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0767-Ab | Cat/Feline | Anti-Cat/Feline LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0767-Ab | Dog/Canine | Anti-Dog/Canine LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0767-Ab | Bovines/Cattle | Anti-Bovines/Cattle LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0767-Ab | Equine/Horse | Anti-Equine/Horse LRRC8A/SWELL1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LRRC8A/SWELL1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0767-Ag | Human | Human LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0767-Ag | Rat | Rat LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0767-Ag | Mouse | Mouse LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0767-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0767-Ag | Cat/Feline | Cat/Feline LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0767-Ag | Dog/Canine | Dog/Canine LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0767-Ag | Bovines/Cattle | Bovines/Cattle LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0767-Ag | Equine/Horse | Equine/Horse LRRC8A/SWELL1 VLP (virus-like particle) | HEK293 | Products Developing |
