Explore KREMEN1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Mutations in this gene result in ectodermal dysplasia. This protein has also been found to be a functional receptor for Coxsackievirus A10 and may be an alternative entry receptor for SARS-CoV-2. [provided by RefSeq, Nov 2021]
| Target ID |
GM-MP0717
|
| Target Name |
KREMEN1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
83999
|
| Gene ID |
100064476 (Equus caballus), 101092648 (Felis catus), 114107 (Rattus norvegicus), 486340 (Canis lupus familiaris)
524357 (Bos taurus), 717359 (Macaca mulatta), 83999 (Homo sapiens), 84035 (Mus musculus)
|
| Target Alternative Names |
Dickkopf receptor,ECTD13,KREMEN,KREMEN1,KRM1,Kremen,Kremen protein 1,Kremen1,Kringle domain-containing transmembrane protein 1,Kringle-containing protein marking the eye and the nose,Krm1
|
| Uniprot Accession |
Q924S4,Q96MU8,Q99N43
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSECAG00000008652, ENSCAFG00845030328, ENSBTAG00000009773, ENSMMUG00000021370, ENSG00000183762, ENSMUSG00000020393
|
KREMEN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo83999 | Pre-made Human KREMEN1/KRM1/ECTD13 siRNA oligo Duplex | 83999 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114107 | Pre-made Rat Kremen1/Kremen siRNA oligo Duplex | 114107 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84035 | Pre-made Mouse Kremen1/Krm1/Kremen siRNA oligo Duplex | 84035 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717359 | Pre-made Cynomolgus/Rhesus macaque KREMEN1 siRNA oligo Duplex | 717359 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092648 | Pre-made Cat/Feline KREMEN1 siRNA oligo Duplex | 101092648 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486340 | Pre-made Dog/Canine KREMEN1 siRNA oligo Duplex | 486340 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524357 | Pre-made Bovines/Cattle KREMEN1 siRNA oligo Duplex | 524357 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064476 | Pre-made Equine/Horse KREMEN1 siRNA oligo Duplex | 100064476 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KREMEN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0717-Ab | Human | Anti-Human KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0717-Ab | Rat | Anti-Rat KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0717-Ab | Mouse | Anti-Mouse KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0717-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0717-Ab | Cat/Feline | Anti-Cat/Feline KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0717-Ab | Dog/Canine | Anti-Dog/Canine KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0717-Ab | Bovines/Cattle | Anti-Bovines/Cattle KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0717-Ab | Equine/Horse | Anti-Equine/Horse KREMEN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
KREMEN1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0717-Ag | Human | Human KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0717-Ag | Rat | Rat KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0717-Ag | Mouse | Mouse KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0717-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0717-Ag | Cat/Feline | Cat/Feline KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0717-Ag | Dog/Canine | Dog/Canine KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0717-Ag | Bovines/Cattle | Bovines/Cattle KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0717-Ag | Equine/Horse | Equine/Horse KREMEN1 VLP (virus-like particle) | HEK293 | Products Developing |
