KL Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore KL gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]

Target ID GM-MP0709
Target Name KL
Gene Group ldentifer
（Target Gene ID in Homo species) 		9365
Gene ID 100064836 (Equus caballus), 100685604 (Canis lupus familiaris), 101082617 (Felis catus), 16591 (Mus musculus)
714042 (Macaca mulatta), 784635 (Bos taurus), 83504 (Rattus norvegicus), 9365 (Homo sapiens)
Target Alternative Names HFTC3,KL,KLA,Kl,Klotho,alpha-kl
Uniprot Accession O35082,Q9Z2Y9,Q9UEF7
Protein Sub-location Transmembrane Protein
Category Cytokine Target
Disease cancer
Disease from KEGG Metabolic pathways, Pentose and glucuronate interconversions, Longevity regulating pathway, Parathyroid hormone synthesis, secretion and action, Ascorbate and aldarate metabolism
Gene Ensembl ENSECAG00000008185, ENSCAFG00845014839, ENSMUSG00000058488, ENSMMUG00000017048, ENSBTAG00000013984, ENSG00000133116


Pre-made viral vector of KL cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV001399Human KL/HFTC3 Lentivirus plasmidNM_004795.49365HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMLV002498Human KL/HFTC3/KLA Lentivirus plasmidNM_004795.49365HumanLentivirus plasmidNull3xflag (C-Terminal)EF1Detail
vGMLV001399Human KL/HFTC3 Lentivirus particleNM_004795.49365HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
vGMLV002498Human KL/HFTC3/KLA Lentivirus particleNM_004795.49365HumanLentivirus particleNull3xflag (C-Terminal)EF1Detail
pGMAD000264Mouse Kl/alpha-kl Adenovirus plasmidNM_01382316591MouseAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMAAV000258Mouse Kl/alpha-kl Adeno-associate virus(AAV) plasmidNM_013823.216591MouseAdeno-associate virus(AAV) plasmidZsGreenNullCMVDetail
pGMPC000632Mouse Kl/alp/alpha-kl Mammalian (Non-Viral Vector) plasmidNM_013823.216591MouseMammalian (Non-Viral Vector) plasmidmCherry3xflag (C-Terminal)CMVDetail
vGMAD000264Mouse Kl/alpha-kl Adenovirus particleNM_01382316591MouseAdenovirus particleNull3xflag (C-Terminal)CMVDetail
vGMAAV000258Mouse Kl/alpha-kl Adeno-associate virus(AAV) particleNM_013823.216591MouseAdeno-associate virus(AAV) particleZsGreenNullCMVDetail


KL siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo9365Pre-made Human KL/KLA/HFTC3 siRNA oligo Duplex9365HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo83504Pre-made Rat Kl siRNA oligo Duplex83504RatIn-vitro grade; in-vivo gradeDetail
pGMoligo16591Pre-made Mouse Kl/alpha-kl siRNA oligo Duplex16591MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo714042Pre-made Cynomolgus/Rhesus macaque KL siRNA oligo Duplex714042Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101082617Pre-made Cat/Feline KL siRNA oligo Duplex101082617Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo100685604Pre-made Dog/Canine KL siRNA oligo Duplex100685604Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo784635Pre-made Bovines/Cattle KL siRNA oligo Duplex784635Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100064836Pre-made Equine/Horse KL siRNA oligo Duplex100064836Equine/HorseIn-vitro grade; in-vivo gradeDetail


KL antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-MP0709-AbHumanAnti-Human KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-rg-MP0709-AbRatAnti-Rat KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-mg-MP0709-AbMouseAnti-Mouse KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-cynog-MP0709-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-felg-MP0709-AbCat/FelineAnti-Cat/Feline KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-cang-MP0709-AbDog/CanineAnti-Dog/Canine KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-bovg-MP0709-AbBovines/CattleAnti-Bovines/Cattle KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-equg-MP0709-AbEquine/HorseAnti-Equine/Horse KL monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail


KL VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-MP0709-AgHumanHuman KL VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-MP0709-AgRatRat KL VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-MP0709-AgMouseMouse KL VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-MP0709-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque KL VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-MP0709-AgCat/FelineCat/Feline KL VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-MP0709-AgDog/CanineDog/Canine KL VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-MP0709-AgBovines/CattleBovines/Cattle KL VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-MP0709-AgEquine/HorseEquine/Horse KL VLP (virus-like particle)HEK293Products Developing