Explore KCNMB2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]
| Target ID |
GM-MP0687
|
| Target Name |
KCNMB2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10242
|
| Gene ID |
100058055 (Equus caballus), 101097911 (Felis catus), 10242 (Homo sapiens), 294961 (Rattus norvegicus)
488179 (Canis lupus familiaris), 534568 (Bos taurus), 710221 (Macaca mulatta), 72413 (Mus musculus)
|
| Target Alternative Names |
2700049B16Rik,3110031N04Rik,BK channel subunit beta-2 (BKbeta2,Calcium-activated potassium channel,Calcium-activated potassium channel subunit beta-2,Charybdotoxin receptor subunit beta-2,Hbeta2),Hbeta3,K(VCA)beta-2,KCNMB2,Kcmb2,Kcnmb2,Maxi K channel subunit beta-2,Slo-beta-2,subfamily M subunit beta-2
|
| Uniprot Accession |
Q9Y691,Q811Q0,Q9CZM9
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Insulin secretion
|
| Gene Ensembl |
ENSECAG00000009088, ENSG00000197584, ENSCAFG00845015513, ENSBTAG00000011377, ENSMMUG00000014426, ENSMUSG00000037610
|
KCNMB2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10242 | Pre-made Human KCNMB2 siRNA oligo Duplex | 10242 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294961 | Pre-made Rat Kcnmb2/Kcmb2 siRNA oligo Duplex | 294961 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo72413 | Pre-made Mouse Kcnmb2/2700049B16Rik/3110031N04Rik siRNA oligo Duplex | 72413 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710221 | Pre-made Cynomolgus/Rhesus macaque KCNMB2 siRNA oligo Duplex | 710221 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097911 | Pre-made Cat/Feline KCNMB2 siRNA oligo Duplex | 101097911 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488179 | Pre-made Dog/Canine KCNMB2 siRNA oligo Duplex | 488179 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534568 | Pre-made Bovines/Cattle KCNMB2 siRNA oligo Duplex | 534568 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058055 | Pre-made Equine/Horse KCNMB2 siRNA oligo Duplex | 100058055 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNMB2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0687-Ab | Human | Anti-Human KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0687-Ab | Rat | Anti-Rat KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0687-Ab | Mouse | Anti-Mouse KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0687-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0687-Ab | Cat/Feline | Anti-Cat/Feline KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0687-Ab | Dog/Canine | Anti-Dog/Canine KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0687-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0687-Ab | Equine/Horse | Anti-Equine/Horse KCNMB2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
KCNMB2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0687-Ag | Human | Human KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0687-Ag | Rat | Rat KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0687-Ag | Mouse | Mouse KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0687-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0687-Ag | Cat/Feline | Cat/Feline KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0687-Ag | Dog/Canine | Dog/Canine KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0687-Ag | Bovines/Cattle | Bovines/Cattle KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0687-Ag | Equine/Horse | Equine/Horse KCNMB2 VLP (virus-like particle) | HEK293 | Products Developing |
