Explore TREK1/KCNK2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0682
|
| Target Name |
TREK1/KCNK2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3776
|
| Gene ID |
100050114 (Equus caballus), 101096695 (Felis catus), 16526 (Mus musculus), 170899 (Rattus norvegicus)
282590 (Bos taurus), 3776 (Homo sapiens), 490295 (Canis lupus familiaris), 708705 (Macaca mulatta)
|
| Target Alternative Names |
KCNK2,Kcnk2,K2P2.1,TREK-1,A430027H14Rik,Trek-1,rTREK1d,TREK,TPKC1,TREK1,K2p2.1,hTREK-1c,hTREK-1e
|
| Uniprot Accession |
P97438,Q920B6,O95069
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Cortisol synthesis and secretion, Cushing syndrome, Gastric acid secretion
|
| Gene Ensembl |
ENSECAG00000023472, ENSMUSG00000037624, ENSBTAG00000004407, ENSG00000082482, ENSMMUG00000016931
|
| Target Classification |
|
Pre-made viral vector of TREK1/KCNK2 cDNA Clones/ORF Plasmid
TREK1/KCNK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3776 | Pre-made Human KCNK2/TREK/TPKC1 siRNA oligo Duplex | 3776 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170899 | Pre-made Rat Kcnk2/Trek-1/rTREK1d siRNA oligo Duplex | 170899 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16526 | Pre-made Mouse Kcnk2/K2P2.1/TREK-1 siRNA oligo Duplex | 16526 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708705 | Pre-made Cynomolgus/Rhesus macaque KCNK2 siRNA oligo Duplex | 708705 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096695 | Pre-made Cat/Feline KCNK2 siRNA oligo Duplex | 101096695 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490295 | Pre-made Dog/Canine KCNK2 siRNA oligo Duplex | 490295 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282590 | Pre-made Bovines/Cattle KCNK2 siRNA oligo Duplex | 282590 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050114 | Pre-made Equine/Horse KCNK2 siRNA oligo Duplex | 100050114 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TREK1/KCNK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0682-Ab | Human | Anti-Human TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0682-Ab | Rat | Anti-Rat TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0682-Ab | Mouse | Anti-Mouse TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0682-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0682-Ab | Cat/Feline | Anti-Cat/Feline TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0682-Ab | Dog/Canine | Anti-Dog/Canine TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0682-Ab | Bovines/Cattle | Anti-Bovines/Cattle TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0682-Ab | Equine/Horse | Anti-Equine/Horse TREK1/KCNK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
TREK1/KCNK2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0682-Ag | Human | Human TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0682-Ag | Rat | Rat TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0682-Ag | Mouse | Mouse TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0682-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0682-Ag | Cat/Feline | Cat/Feline TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0682-Ag | Dog/Canine | Dog/Canine TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0682-Ag | Bovines/Cattle | Bovines/Cattle TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0682-Ag | Equine/Horse | Equine/Horse TREK1/KCNK2 VLP (virus-like particle) | HEK293 | Products Developing |
