Explore Jagged1/JAG1/CD339 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Nov 2019]
| Target ID |
GM-MP0648
|
| Target Name |
Jagged1/JAG1/CD339
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
182
|
| Gene ID |
100064289 (Equus caballus), 101093427 (Felis catus), 16449 (Mus musculus), 182 (Homo sapiens)
29146 (Rattus norvegicus), 485769 (Canis lupus familiaris), 718580 (Macaca mulatta), 783681 (Bos taurus)
|
| Target Alternative Names |
ABE2,AGS,AGS1,AHD,AWS,CD339,CMT2HH,DCHE,Gena228,Gsfabe2,HJ1,Htu,JAG1,JAGL1,Jag1,Jagged1,Ozz,Protein jagged-1,Ser-1,hJ1
|
| Uniprot Accession |
Q9QXX0,P78504,Q63722
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
Endocrine resistance, Th1 and Th2 cell differentiation, TNF signaling pathway, Human papillomavirus infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer
|
| Gene Ensembl |
ENSECAG00000012993, ENSMUSG00000027276, ENSG00000101384, ENSCAFG00845024085, ENSMMUG00000018116, ENSBTAG00000012817
|
Pre-made viral vector of Jagged1/JAG1/CD339 cDNA Clones/ORF Plasmid
Jagged1/JAG1/CD339 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo182 | Pre-made Human JAG1/AGS/AHD siRNA oligo Duplex | 182 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29146 | Pre-made Rat Jag1 siRNA oligo Duplex | 29146 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16449 | Pre-made Mouse Jag1/Htu/Ozz siRNA oligo Duplex | 16449 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718580 | Pre-made Cynomolgus/Rhesus macaque JAG1 siRNA oligo Duplex | 718580 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093427 | Pre-made Cat/Feline JAG1 siRNA oligo Duplex | 101093427 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485769 | Pre-made Dog/Canine JAG1 siRNA oligo Duplex | 485769 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo783681 | Pre-made Bovines/Cattle JAG1 siRNA oligo Duplex | 783681 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064289 | Pre-made Equine/Horse JAG1 siRNA oligo Duplex | 100064289 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Jagged1/JAG1/CD339 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0648-Ab | Human | Anti-Human Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0648-Ab | Rat | Anti-Rat Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0648-Ab | Mouse | Anti-Mouse Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0648-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0648-Ab | Cat/Feline | Anti-Cat/Feline Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0648-Ab | Dog/Canine | Anti-Dog/Canine Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0648-Ab | Bovines/Cattle | Anti-Bovines/Cattle Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0648-Ab | Equine/Horse | Anti-Equine/Horse Jagged1/JAG1/CD339 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Jagged1/JAG1/CD339 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0648-Ag | Human | Human Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0648-Ag | Rat | Rat Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0648-Ag | Mouse | Mouse Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0648-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0648-Ag | Cat/Feline | Cat/Feline Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0648-Ag | Dog/Canine | Dog/Canine Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0648-Ag | Bovines/Cattle | Bovines/Cattle Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0648-Ag | Equine/Horse | Equine/Horse Jagged1/JAG1/CD339 VLP (virus-like particle) | HEK293 | Products Developing |
