Explore Integrin Beta 4/ITGB4/CD104 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0639
|
| Target Name |
Integrin Beta 4/ITGB4/CD104
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3691
|
| Gene ID |
100051679 (Equus caballus), 101080415 (Felis catus), 192897 (Mus musculus), 25724 (Rattus norvegicus)
3691 (Homo sapiens), 483318 (Canis lupus familiaris), 506995 (Bos taurus), 703770 (Macaca mulatta)
|
| Target Alternative Names |
ITGB4,Itgb4,CD104,C230078O20,GP150,JEB5A,JEB5B
|
| Uniprot Accession |
A2A863,Q64632,P16144
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
cancer
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Regulation of actin cytoskeleton, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000010178, ENSMUSG00000020758, ENSG00000132470, ENSCAFG00845024014, ENSBTAG00000018169, ENSMMUG00000021763
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Integrin Beta 4/ITGB4/CD104 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3691 | Pre-made Human ITGB4/CD104/GP150 siRNA oligo Duplex | 3691 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25724 | Pre-made Rat Itgb4 siRNA oligo Duplex | 25724 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo192897 | Pre-made Mouse Itgb4/CD104/C230078O20 siRNA oligo Duplex | 192897 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703770 | Pre-made Cynomolgus/Rhesus macaque ITGB4 siRNA oligo Duplex | 703770 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080415 | Pre-made Cat/Feline ITGB4 siRNA oligo Duplex | 101080415 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483318 | Pre-made Dog/Canine ITGB4 siRNA oligo Duplex | 483318 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506995 | Pre-made Bovines/Cattle ITGB4 siRNA oligo Duplex | 506995 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051679 | Pre-made Equine/Horse ITGB4 siRNA oligo Duplex | 100051679 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Integrin Beta 4/ITGB4/CD104 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0639-Ab | Human | Anti-Human Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0639-Ab | Rat | Anti-Rat Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0639-Ab | Mouse | Anti-Mouse Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0639-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0639-Ab | Cat/Feline | Anti-Cat/Feline Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0639-Ab | Dog/Canine | Anti-Dog/Canine Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0639-Ab | Bovines/Cattle | Anti-Bovines/Cattle Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0639-Ab | Equine/Horse | Anti-Equine/Horse Integrin Beta 4/ITGB4/CD104 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0639-Ag | Human | Human Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0639-Ag | Rat | Rat Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0639-Ag | Mouse | Mouse Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0639-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0639-Ag | Cat/Feline | Cat/Feline Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0639-Ag | Dog/Canine | Dog/Canine Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0639-Ag | Bovines/Cattle | Bovines/Cattle Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0639-Ag | Equine/Horse | Equine/Horse Integrin Beta 4/ITGB4/CD104 VLP (virus-like particle) | HEK293 | Products Developing |
