Explore CD11c/Integrin Alpha X/ITGAX gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
| Target ID |
GM-MP0638
|
| Target Name |
CD11c/Integrin Alpha X/ITGAX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3687
|
| Gene ID |
100427850 (Macaca mulatta), 101087698 (Felis catus), 16411 (Mus musculus), 3687 (Homo sapiens)
489929 (Canis lupus familiaris), 499271 (Rattus norvegicus)
|
| Target Alternative Names |
95,95 alpha chain,CD11 antigen-like family member C,CD11C,CD11c,Cd11c,Cr4,ITGAX,Integrin Alpha X,Integrin alpha-X,Itgax,Leu M5,Leukocyte adhesion glycoprotein p150,Leukocyte adhesion receptor p150,N418,RGD1561123,SLEB6
|
| Uniprot Accession |
Q9QXH4,P20702
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Complement and coagulation cascades, Regulation of actin cytoskeleton, Tuberculosis
|
| Gene Ensembl |
ENSMMUG00000014349, ENSMUSG00000030789, ENSG00000140678, ENSCAFG00845010970
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD11c/Integrin Alpha X/ITGAX cDNA Clones/ORF Plasmid
CD11c/Integrin Alpha X/ITGAX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3687 | Pre-made Human ITGAX/CD11C/SLEB6 siRNA oligo Duplex | 3687 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo499271 | Pre-made Rat Itgax/RGD1561123 siRNA oligo Duplex | 499271 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16411 | Pre-made Mouse Itgax/Cr4/N418 siRNA oligo Duplex | 16411 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100427850 | Pre-made Cynomolgus/Rhesus macaque ITGAX siRNA oligo Duplex | 100427850 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087698 | Pre-made Cat/Feline ITGAX siRNA oligo Duplex | 101087698 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489929 | Pre-made Dog/Canine ITGAX siRNA oligo Duplex | 489929 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
CD11c/Integrin Alpha X/ITGAX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0638-Ab | Human | Anti-Human CD11c/Integrin Alpha X/ITGAX monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0638-Ab | Rat | Anti-Rat CD11c/Integrin Alpha X/ITGAX monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0638-Ab | Mouse | Anti-Mouse CD11c/Integrin Alpha X/ITGAX monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0638-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD11c/Integrin Alpha X/ITGAX monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0638-Ab | Cat/Feline | Anti-Cat/Feline CD11c/Integrin Alpha X/ITGAX monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0638-Ab | Dog/Canine | Anti-Dog/Canine CD11c/Integrin Alpha X/ITGAX monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD11c/Integrin Alpha X/ITGAX VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0638-Ag | Human | Human CD11c/Integrin Alpha X/ITGAX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0638-Ag | Rat | Rat CD11c/Integrin Alpha X/ITGAX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0638-Ag | Mouse | Mouse CD11c/Integrin Alpha X/ITGAX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0638-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD11c/Integrin Alpha X/ITGAX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0638-Ag | Cat/Feline | Cat/Feline CD11c/Integrin Alpha X/ITGAX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0638-Ag | Dog/Canine | Dog/Canine CD11c/Integrin Alpha X/ITGAX VLP (virus-like particle) | HEK293 | Products Developing |
