Explore ITGA7 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009]
Target ID |
GM-MP0635
|
Target Name |
ITGA7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3679
|
Gene ID |
100058756 (Equus caballus), 101089783 (Felis catus), 16404 (Mus musculus), 3679 (Homo sapiens) 481097 (Canis lupus familiaris), 506953 (Bos taurus), 707279 (Macaca mulatta), 81008 (Rattus norvegicus)
|
Target Alternative Names |
ITGA7,Itga7,[a]7,alpha7
|
Uniprot Accession |
Q61738,Q13683,Q63258
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Therapeutics Target, INN Index
|
Disease |
|
Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Regulation of actin cytoskeleton, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
Gene Ensembl |
ENSECAG00000011735, ENSMUSG00000025348, ENSG00000135424, ENSCAFG00845005303, ENSBTAG00000012897, ENSMMUG00000013226
|
Target Classification |
|
ITGA7 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo3679 | Pre-made Human ITGA7 siRNA oligo Duplex | 3679 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo81008 | Pre-made Rat Itga7 siRNA oligo Duplex | 81008 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo16404 | Pre-made Mouse Itga7/[a]7/alpha7 siRNA oligo Duplex | 16404 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo707279 | Pre-made Cynomolgus/Rhesus macaque ITGA7 siRNA oligo Duplex | 707279 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101089783 | Pre-made Cat/Feline ITGA7 siRNA oligo Duplex | 101089783 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo481097 | Pre-made Dog/Canine ITGA7 siRNA oligo Duplex | 481097 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo506953 | Pre-made Bovines/Cattle ITGA7 siRNA oligo Duplex | 506953 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100058756 | Pre-made Equine/Horse ITGA7 siRNA oligo Duplex | 100058756 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ITGA7 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-MP0635-Ab | Human | Anti-Human ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-rg-MP0635-Ab | Rat | Anti-Rat ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-mg-MP0635-Ab | Mouse | Anti-Mouse ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-MP0635-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-felg-MP0635-Ab | Cat/Feline | Anti-Cat/Feline ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cang-MP0635-Ab | Dog/Canine | Anti-Dog/Canine ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-MP0635-Ab | Bovines/Cattle | Anti-Bovines/Cattle ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-MP0635-Ab | Equine/Horse | Anti-Equine/Horse ITGA7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ITGA7 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-MP0635-Ag | Human | Human ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-MP0635-Ag | Rat | Rat ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-MP0635-Ag | Mouse | Mouse ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-MP0635-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-MP0635-Ag | Cat/Feline | Cat/Feline ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-MP0635-Ag | Dog/Canine | Dog/Canine ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-MP0635-Ag | Bovines/Cattle | Bovines/Cattle ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-MP0635-Ag | Equine/Horse | Equine/Horse ITGA7 VLP (virus-like particle) | HEK293 | Products Developing |