Explore Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
| Target ID |
GM-MP0634
|
| Target Name |
Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3675
|
| Gene ID |
100056202 (Equus caballus), 101093156 (Felis catus), 16400 (Mus musculus), 360606 (Rattus norvegicus) 3675 (Homo sapiens), 491074 (Canis lupus familiaris), 508490 (Bos taurus), 700962 (Macaca mulatta)
|
| Target Alternative Names |
CD49 antigen-like family member C,CD49C,CD49c,FRP-2,GAP-B3,GAPB3,Galactoprotein B3 (GAPB3),ILNEB,ITGA3,Integrin Alpha 3,Integrin alpha-3,Itga3,JEB7,MSK18,VCA-2,VL3A,VLA-3 subunit alpha,VLA3a
|
| Uniprot Accession |
Q62470,P26006,F1MMS9
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Kidney transplant rejection, Malignant neoplasm of prostate
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000015760, ENSMUSG00000001507, ENSG00000005884, ENSCAFG00845011823, ENSBTAG00000019498, ENSMMUG00000000153
|
Pre-made viral vector of Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c cDNA Clones/ORF Plasmid
Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3675 | Pre-made Human ITGA3/JEB7/VL3A siRNA oligo Duplex | 3675 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360606 | Pre-made Rat Itga3 siRNA oligo Duplex | 360606 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16400 | Pre-made Mouse Itga3/CD49C/GAPB3 siRNA oligo Duplex | 16400 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700962 | Pre-made Cynomolgus/Rhesus macaque ITGA3 siRNA oligo Duplex | 700962 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093156 | Pre-made Cat/Feline ITGA3 siRNA oligo Duplex | 101093156 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491074 | Pre-made Dog/Canine ITGA3 siRNA oligo Duplex | 491074 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508490 | Pre-made Bovines/Cattle ITGA3/GAPB3 siRNA oligo Duplex | 508490 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056202 | Pre-made Equine/Horse ITGA3 siRNA oligo Duplex | 100056202 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0634-Ab | Human | Anti-Human Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0634-Ab | Rat | Anti-Rat Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0634-Ab | Mouse | Anti-Mouse Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0634-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0634-Ab | Cat/Feline | Anti-Cat/Feline Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0634-Ab | Dog/Canine | Anti-Dog/Canine Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0634-Ab | Bovines/Cattle | Anti-Bovines/Cattle Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0634-Ab | Equine/Horse | Anti-Equine/Horse Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0634-Ag | Human | Human Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0634-Ag | Rat | Rat Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0634-Ag | Mouse | Mouse Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0634-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0634-Ag | Cat/Feline | Cat/Feline Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0634-Ag | Dog/Canine | Dog/Canine Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0634-Ag | Bovines/Cattle | Bovines/Cattle Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0634-Ag | Equine/Horse | Equine/Horse Integrin Alpha 3/Integrin alpha-3/ITGA3/CD49c VLP (virus-like particle) | HEK293 | Products Developing |