Explore IL-2RG/IL2RG/CD132 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]
| Target ID |
GM-MP0627
|
| Target Name |
IL-2RG/IL2RG/CD132
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3561
|
| Gene ID |
100055911 (Equus caballus), 101090239 (Felis catus), 140924 (Rattus norvegicus), 16186 (Mus musculus)
281862 (Bos taurus), 3561 (Homo sapiens), 403851 (Canis lupus familiaris), 641338 (Macaca mulatta)
|
| Target Alternative Names |
Ab2-183,CD132,CIDX,Cd132,Cytokine receptor common subunit gamma,IL-2R subunit gamma,IL-2RG,IL-2RG),IL2RG,IMD4,Il2rg,Interleukin-2 receptor subunit gamma (IL-2 receptor subunit gamma,P64,SCIDX,SCIDX1,[g]c,gamma(c),gammaC,gc,p64
|
| Uniprot Accession |
P34902,Q95118,P31785,P40321
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer, Inflammatory bowel disease
|
| Gene Ensembl |
ENSECAG00000016543, ENSMUSG00000031304, ENSBTAG00000007626, ENSG00000147168, ENSCAFG00845017057, ENSMMUG00000017795
|
| Target Classification |
Cytokine Receptor, Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-2RG/IL2RG/CD132 cDNA Clones/ORF Plasmid
IL-2RG/IL2RG/CD132 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3561 | Pre-made Human IL2RG/P64/CIDX siRNA oligo Duplex | 3561 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo140924 | Pre-made Rat Il2rg/Cd132/Ab2-183 siRNA oligo Duplex | 140924 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16186 | Pre-made Mouse Il2rg/gc/p64 siRNA oligo Duplex | 16186 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo641338 | Pre-made Cynomolgus/Rhesus macaque IL2RG siRNA oligo Duplex | 641338 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090239 | Pre-made Cat/Feline IL2RG siRNA oligo Duplex | 101090239 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403851 | Pre-made Dog/Canine IL2RG siRNA oligo Duplex | 403851 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281862 | Pre-made Bovines/Cattle IL2RG siRNA oligo Duplex | 281862 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055911 | Pre-made Equine/Horse IL2RG siRNA oligo Duplex | 100055911 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-2RG/IL2RG/CD132 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0627-Ab | Human | Anti-Human IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0627-Ab | Rat | Anti-Rat IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0627-Ab | Mouse | Anti-Mouse IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0627-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0627-Ab | Cat/Feline | Anti-Cat/Feline IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0627-Ab | Dog/Canine | Anti-Dog/Canine IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0627-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0627-Ab | Equine/Horse | Anti-Equine/Horse IL-2RG/IL2RG/CD132 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
IL-2RG/IL2RG/CD132 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0627-Ag | Human | Human IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0627-Ag | Rat | Rat IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0627-Ag | Mouse | Mouse IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0627-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0627-Ag | Cat/Feline | Cat/Feline IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0627-Ag | Dog/Canine | Dog/Canine IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0627-Ag | Bovines/Cattle | Bovines/Cattle IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0627-Ag | Equine/Horse | Equine/Horse IL-2RG/IL2RG/CD132 VLP (virus-like particle) | HEK293 | Products Developing |
