Explore IL-22RA2/IL22RA2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
| Target ID |
GM-MP0626
|
| Target Name |
IL-22RA2/IL22RA2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
116379
|
| Gene ID |
100073194 (Equus caballus), 100856046 (Canis lupus familiaris), 101083429 (Felis catus), 116379 (Homo sapiens) 237310 (Mus musculus), 444986 (Rattus norvegicus), 533061 (Bos taurus), 711059 (Macaca mulatta)
|
| Target Alternative Names |
CRF2-10,CRF2-S1,CRF2-s1,CRF2X,Crf2-s1,Cytokine receptor class-II member 10,Cytokine receptor family 2 member 10 (CRF2-10),Cytokine receptor family type 2,IL-22 receptor subunit alpha-2,IL-22BP,IL-22R-alpha-2,IL-22RA2,IL22BP),IL22RA2,Il-22bp,Il22ra2,Interleukin-22 receptor subunit alpha-2,Interleukin-22-binding protein (IL-22BP,ZCYTOR16,ZcytoR16,soluble 1 (CRF2-S1)
|
| Uniprot Accession |
Q969J5,Q80XF5,Q7TNI4
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease from KEGG |
JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSECAG00000008817, ENSCAFG00845006505, ENSG00000164485, ENSMUSG00000039760, ENSBTAG00000017000, ENSMMUG00000013562
|
IL-22RA2/IL22RA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo116379 | Pre-made Human IL22RA2/CRF2X/CRF2-10 siRNA oligo Duplex | 116379 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo444986 | Pre-made Rat Il22ra2/Crf2-s1 siRNA oligo Duplex | 444986 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo237310 | Pre-made Mouse Il22ra2/CRF2X/CRF2-10 siRNA oligo Duplex | 237310 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711059 | Pre-made Cynomolgus/Rhesus macaque IL22RA2 siRNA oligo Duplex | 711059 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083429 | Pre-made Cat/Feline IL22RA2 siRNA oligo Duplex | 101083429 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856046 | Pre-made Dog/Canine IL22RA2 siRNA oligo Duplex | 100856046 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533061 | Pre-made Bovines/Cattle IL22RA2 siRNA oligo Duplex | 533061 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073194 | Pre-made Equine/Horse IL22RA2 siRNA oligo Duplex | 100073194 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-22RA2/IL22RA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0626-Ab | Human | Anti-Human IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0626-Ab | Rat | Anti-Rat IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0626-Ab | Mouse | Anti-Mouse IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0626-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0626-Ab | Cat/Feline | Anti-Cat/Feline IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0626-Ab | Dog/Canine | Anti-Dog/Canine IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0626-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0626-Ab | Equine/Horse | Anti-Equine/Horse IL-22RA2/IL22RA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL-22RA2/IL22RA2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0626-Ag | Human | Human IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0626-Ag | Rat | Rat IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0626-Ag | Mouse | Mouse IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0626-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0626-Ag | Cat/Feline | Cat/Feline IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0626-Ag | Dog/Canine | Dog/Canine IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0626-Ag | Bovines/Cattle | Bovines/Cattle IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0626-Ag | Equine/Horse | Equine/Horse IL-22RA2/IL22RA2 VLP (virus-like particle) | HEK293 | Products Developing |