Explore IL-1RL1/ST2/IL1RL1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0622
|
| Target Name |
IL-1RL1/ST2/IL1RL1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9173
|
| Gene ID |
100058357 (Equus caballus), 101080448 (Felis catus), 17082 (Mus musculus), 25556 (Rattus norvegicus) 520709 (Bos taurus), 611442 (Canis lupus familiaris), 711893 (Macaca mulatta), 9173 (Homo sapiens)
|
| Target Alternative Names |
DER4,FIT-1,FIT1,Fit-1,IL-1RL1,IL1RL1,IL33R,Il1rl1,Interleukin-1 receptor-like 1,Ly84,Protein ST2,ST2,ST2L,ST2V,St2,St2-rs1,T1,T1/ST2
|
| Uniprot Accession |
P14719,Q62611,Q01638
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000009248, ENSMUSG00000026069, ENSBTAG00000018571, ENSCAFG00845010486, ENSMMUG00000009238, ENSG00000115602
|
| Target Classification |
Cytokine Receptor, Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-1RL1/ST2/IL1RL1 cDNA Clones/ORF Plasmid
IL-1RL1/ST2/IL1RL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9173 | Pre-made Human IL1RL1/T1/ST2 siRNA oligo Duplex | 9173 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25556 | Pre-made Rat Il1rl1/St2/FIT1 siRNA oligo Duplex | 25556 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17082 | Pre-made Mouse Il1rl1/T1/St2 siRNA oligo Duplex | 17082 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711893 | Pre-made Cynomolgus/Rhesus macaque IL1RL1 siRNA oligo Duplex | 711893 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080448 | Pre-made Cat/Feline IL1RL1 siRNA oligo Duplex | 101080448 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611442 | Pre-made Dog/Canine IL1RL1 siRNA oligo Duplex | 611442 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520709 | Pre-made Bovines/Cattle IL1RL1 siRNA oligo Duplex | 520709 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058357 | Pre-made Equine/Horse IL1RL1 siRNA oligo Duplex | 100058357 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1RL1/ST2/IL1RL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0622-Ab | Human | Anti-Human IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0622-Ab | Rat | Anti-Rat IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0622-Ab | Mouse | Anti-Mouse IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0622-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0622-Ab | Cat/Feline | Anti-Cat/Feline IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0622-Ab | Dog/Canine | Anti-Dog/Canine IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0622-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0622-Ab | Equine/Horse | Anti-Equine/Horse IL-1RL1/ST2/IL1RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-1RL1/ST2/IL1RL1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0622-Ag | Human | Human IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0622-Ag | Rat | Rat IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0622-Ag | Mouse | Mouse IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0622-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0622-Ag | Cat/Feline | Cat/Feline IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0622-Ag | Dog/Canine | Dog/Canine IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0622-Ag | Bovines/Cattle | Bovines/Cattle IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0622-Ag | Equine/Horse | Equine/Horse IL-1RL1/ST2/IL1RL1 VLP (virus-like particle) | HEK293 | Products Developing |