Explore IL-1-RAPL-1/IL1RAPL1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]
Target ID |
GM-MP0620
|
Target Name |
IL-1-RAPL-1/IL1RAPL1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
11141
|
Gene ID |
100052404 (Equus caballus), 101082883 (Felis catus), 11141 (Homo sapiens), 317553 (Rattus norvegicus) 331461 (Mus musculus), 491800 (Canis lupus familiaris), 541298 (Bos taurus), 706588 (Macaca mulatta)
|
Target Alternative Names |
IL1RAPL1,Il1rapl1,IL1R8,MRX10,MRX21,MRX34,OPHN4,IL1RAPL,TIGIRR-2,IL1RAPL-1,IL-1RAPL-1,IL-1-RAPL-1,Il1rapl,C030039N24,6330532G10Rik
|
Uniprot Accession |
Q9NZN1,P59824,P59823
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Cytokine Target
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000016331, ENSG00000169306, ENSMUSG00000052372, ENSCAFG00845030922,ENSCAFG00845030937, ENSBTAG00000053869, ENSMMUG00000001663
|
Target Classification |
|
IL-1-RAPL-1/IL1RAPL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo11141 | Pre-made Human IL1RAPL1/IL1R8/MRX10 siRNA oligo Duplex | 11141 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo317553 | Pre-made Rat Il1rapl1/Il1rapl siRNA oligo Duplex | 317553 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo331461 | Pre-made Mouse Il1rapl1/IL1R8/MRX34 siRNA oligo Duplex | 331461 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo706588 | Pre-made Cynomolgus/Rhesus macaque IL1RAPL1 siRNA oligo Duplex | 706588 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101082883 | Pre-made Cat/Feline IL1RAPL1 siRNA oligo Duplex | 101082883 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo491800 | Pre-made Dog/Canine IL1RAPL1 siRNA oligo Duplex | 491800 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo541298 | Pre-made Bovines/Cattle IL1RAPL1 siRNA oligo Duplex | 541298 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100052404 | Pre-made Equine/Horse IL1RAPL1 siRNA oligo Duplex | 100052404 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1-RAPL-1/IL1RAPL1 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-MP0620-Ab | Human | Anti-Human IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GM-Tg-rg-MP0620-Ab | Rat | Anti-Rat IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GM-Tg-mg-MP0620-Ab | Mouse | Anti-Mouse IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GM-Tg-cynog-MP0620-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GM-Tg-felg-MP0620-Ab | Cat/Feline | Anti-Cat/Feline IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GM-Tg-cang-MP0620-Ab | Dog/Canine | Anti-Dog/Canine IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GM-Tg-bovg-MP0620-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GM-Tg-equg-MP0620-Ab | Equine/Horse | Anti-Equine/Horse IL-1-RAPL-1/IL1RAPL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-MP0620-Ag | Human | Human IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-MP0620-Ag | Rat | Rat IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-MP0620-Ag | Mouse | Mouse IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-MP0620-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-MP0620-Ag | Cat/Feline | Cat/Feline IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-MP0620-Ag | Dog/Canine | Dog/Canine IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-MP0620-Ag | Bovines/Cattle | Bovines/Cattle IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-MP0620-Ag | Equine/Horse | Equine/Horse IL-1-RAPL-1/IL1RAPL1 VLP (virus-like particle) | HEK293 | Products Developing |