Explore IL-18R1/IL18R1/CD218a gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
| Target ID |
GM-MP0619
|
| Target Name |
IL-18R1/IL18R1/CD218a
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8809
|
| Gene ID |
100058269 (Equus caballus), 100426588 (Macaca mulatta), 16182 (Mus musculus), 301365 (Rattus norvegicus)
407221 (Bos taurus), 493938 (Felis catus), 611438 (Canis lupus familiaris), 8809 (Homo sapiens)
|
| Target Alternative Names |
CD218 antigen-like family member A,CD218a,CDw218a,IL-18R-1,IL-18R-alpha,IL-18R1,IL-18Ra,IL-18Ralpha,IL-18Ralpha),IL-1Rrp,IL1 receptor-related protein (IL-1Rrp,IL18R1,IL18RA,IL18Ralpha2,IL1R-rp),IL1RRP,Il18r1,Il18ralpha,Il1rrp,Interleukin-18 receptor 1,Interleukin-18 receptor alpha (IL-18R-alpha
|
| Uniprot Accession |
Q61098,Q13478
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Inflammatory bowel disease
|
| Gene Ensembl |
ENSMMUG00000009244, ENSMUSG00000026070, ENSBTAG00000001034, ENSCAFG00845010486, ENSG00000115604
|
| Target Classification |
Cytokine Receptor
|
Pre-made viral vector of IL-18R1/IL18R1/CD218a cDNA Clones/ORF Plasmid
IL-18R1/IL18R1/CD218a siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8809 | Pre-made Human IL18R1/CD218a/IL18RA siRNA oligo Duplex | 8809 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301365 | Pre-made Rat Il18r1 siRNA oligo Duplex | 301365 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16182 | Pre-made Mouse Il18r1/Il1rrp/Il18ralpha siRNA oligo Duplex | 16182 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100426588 | Pre-made Cynomolgus/Rhesus macaque IL18R1 siRNA oligo Duplex | 100426588 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493938 | Pre-made Cat/Feline IL18R1 siRNA oligo Duplex | 493938 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611438 | Pre-made Dog/Canine IL18R1 siRNA oligo Duplex | 611438 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407221 | Pre-made Bovines/Cattle IL18R1/IL-18Ra siRNA oligo Duplex | 407221 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058269 | Pre-made Equine/Horse IL18R1 siRNA oligo Duplex | 100058269 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-18R1/IL18R1/CD218a antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0619-Ab | Human | Anti-Human IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0619-Ab | Rat | Anti-Rat IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0619-Ab | Mouse | Anti-Mouse IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0619-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0619-Ab | Cat/Feline | Anti-Cat/Feline IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0619-Ab | Dog/Canine | Anti-Dog/Canine IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0619-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0619-Ab | Equine/Horse | Anti-Equine/Horse IL-18R1/IL18R1/CD218a monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL-18R1/IL18R1/CD218a VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0619-Ag | Human | Human IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0619-Ag | Rat | Rat IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0619-Ag | Mouse | Mouse IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0619-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0619-Ag | Cat/Feline | Cat/Feline IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0619-Ag | Dog/Canine | Dog/Canine IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0619-Ag | Bovines/Cattle | Bovines/Cattle IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0619-Ag | Equine/Horse | Equine/Horse IL-18R1/IL18R1/CD218a VLP (virus-like particle) | HEK293 | Products Developing |
