Explore IGSF8/CD316 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
| Target ID |
GM-MP0616
|
| Target Name |
IGSF8/CD316
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
93185
|
| Gene ID |
100058209 (Equus caballus), 100855523 (Canis lupus familiaris), 101097041 (Felis catus), 140559 (Mus musculus)
304979 (Rattus norvegicus), 519266 (Bos taurus), 720186 (Macaca mulatta), 93185 (Homo sapiens)
|
| Target Alternative Names |
CD316,CD81 partner 3,CD81P3,ESTM34,EWI-2,EWI2,Glu-Trp-Ile EWI motif-containing protein 2 (EWI-2),IGSF8,IgSF8,Igsf8,Immunoglobulin superfamily member 8,KCT-4,Keratinocytes-associated transmembrane protein 4 (KCT-4),LIR-D1,PGRL,Prostaglandin regulatory-like protein (PGRL)
|
| Uniprot Accession |
Q8R366,Q969P0
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSECAG00000022195, ENSCAFG00845030820, ENSMUSG00000038034, ENSBTAG00000009982, ENSMMUG00000031542, ENSG00000162729
|
Pre-made viral vector of IGSF8/CD316 cDNA Clones/ORF Plasmid
IGSF8/CD316 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo93185 | Pre-made Human IGSF8/EWI2/PGRL siRNA oligo Duplex | 93185 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo304979 | Pre-made Rat Igsf8 siRNA oligo Duplex | 304979 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo140559 | Pre-made Mouse Igsf8/PGRL/EWI-2 siRNA oligo Duplex | 140559 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720186 | Pre-made Cynomolgus/Rhesus macaque IGSF8 siRNA oligo Duplex | 720186 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097041 | Pre-made Cat/Feline IGSF8 siRNA oligo Duplex | 101097041 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100855523 | Pre-made Dog/Canine IGSF8 siRNA oligo Duplex | 100855523 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo519266 | Pre-made Bovines/Cattle IGSF8 siRNA oligo Duplex | 519266 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058209 | Pre-made Equine/Horse IGSF8 siRNA oligo Duplex | 100058209 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGSF8/CD316 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0616-Ab | Human | Anti-Human IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0616-Ab | Rat | Anti-Rat IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0616-Ab | Mouse | Anti-Mouse IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0616-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0616-Ab | Cat/Feline | Anti-Cat/Feline IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0616-Ab | Dog/Canine | Anti-Dog/Canine IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0616-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0616-Ab | Equine/Horse | Anti-Equine/Horse IGSF8/CD316 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
IGSF8/CD316 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0616-Ag | Human | Human IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0616-Ag | Rat | Rat IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0616-Ag | Mouse | Mouse IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0616-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0616-Ag | Cat/Feline | Cat/Feline IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0616-Ag | Dog/Canine | Dog/Canine IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0616-Ag | Bovines/Cattle | Bovines/Cattle IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0616-Ag | Equine/Horse | Equine/Horse IGSF8/CD316 VLP (virus-like particle) | HEK293 | Products Developing |
