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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0607
|
| Target Name |
IL28RA/IFNLR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
163702
|
| Gene ID |
100057607 (Equus caballus), 101097499 (Felis catus), 163702 (Homo sapiens), 242700 (Mus musculus)
362628 (Rattus norvegicus), 612276 (Canis lupus familiaris), 616826 (Bos taurus), 711625 (Macaca mulatta)
|
| Target Alternative Names |
CRF2-12,CRF2/12,Cytokine receptor class-II member 12,Cytokine receptor family 2 member 12 (CRF2-12),IFN-lambda receptor 1,IFN-lambda-R1,IFNLR,IFNLR1,IL-28R-alpha,IL-28R1,IL-28RA),IL28RA,Ifnlr1,Il28ra,Interferon lambda receptor 1,Interleukin-28 receptor subunit alpha (IL-28 receptor subunit alpha,LICR2,Likely interleukin or cytokine receptor 2 (LICR2),RGD1562689
|
| Uniprot Accession |
Q8IU57,Q8CGK5
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSECAG00000013289, ENSG00000185436, ENSMUSG00000062157, ENSBTAG00000001101, ENSMMUG00000023057
|
| Target Classification |
Cytokine Receptor
|
Pre-made viral vector of IL28RA/IFNLR1 cDNA Clones/ORF Plasmid
IL28RA/IFNLR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo163702 | Pre-made Human IFNLR1/IFNLR/LICR2 siRNA oligo Duplex | 163702 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362628 | Pre-made Rat Ifnlr1/Il28ra/RGD1562689 siRNA oligo Duplex | 362628 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo242700 | Pre-made Mouse Ifnlr1/Il28ra/CRF2-12 siRNA oligo Duplex | 242700 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711625 | Pre-made Cynomolgus/Rhesus macaque IFNLR1/IL28RA siRNA oligo Duplex | 711625 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097499 | Pre-made Cat/Feline IFNLR1/IL28RA siRNA oligo Duplex | 101097499 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612276 | Pre-made Dog/Canine IFNLR1/IL28RA siRNA oligo Duplex | 612276 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616826 | Pre-made Bovines/Cattle IFNLR1/IL28RA siRNA oligo Duplex | 616826 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057607 | Pre-made Equine/Horse IFNLR1 siRNA oligo Duplex | 100057607 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL28RA/IFNLR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0607-Ab | Human | Anti-Human IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0607-Ab | Rat | Anti-Rat IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0607-Ab | Mouse | Anti-Mouse IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0607-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0607-Ab | Cat/Feline | Anti-Cat/Feline IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0607-Ab | Dog/Canine | Anti-Dog/Canine IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0607-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0607-Ab | Equine/Horse | Anti-Equine/Horse IL28RA/IFNLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL28RA/IFNLR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0607-Ag | Human | Human IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0607-Ag | Rat | Rat IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0607-Ag | Mouse | Mouse IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0607-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0607-Ag | Cat/Feline | Cat/Feline IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0607-Ag | Dog/Canine | Dog/Canine IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0607-Ag | Bovines/Cattle | Bovines/Cattle IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0607-Ag | Equine/Horse | Equine/Horse IL28RA/IFNLR1 VLP (virus-like particle) | HEK293 | Products Developing |
