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Target
sublocation: Transmembrane Protein.
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0590
|
| Target Name |
HLA-G
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3135
|
| Gene ID |
3135 (Homo sapiens)
|
| Target Alternative Names |
HLA G antigen,HLA class I histocompatibility antigen,HLA-G,MHC class I antigen G,MHC-G,alpha chain G
|
| Uniprot Accession |
P17693
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
Phagosome, Cellular senescence, Cell adhesion molecules, Antigen processing and presentation, Type I diabetes mellitus, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Autoimmune thyroid disease, Allograft rejection, Graft-versus-host disease, Viral myocarditis
|
| Gene Ensembl |
ENSG00000204632
|
Pre-made viral vector of HLA-G cDNA Clones/ORF Plasmid
HLA-G siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3135 | Pre-made Human HLA-G/MHC-G siRNA oligo Duplex | 3135 | Human | In-vitro grade; in-vivo grade | Detail |
HLA-G antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0590-Ab | Human | Anti-Human HLA-G monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
HLA-G VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0590-Ag | Human | Human HLA-G VLP (virus-like particle) | HEK293 | Products Developing |
