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Target
sublocation: Transmembrane Protein.
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]
| Target ID |
GM-MP0585
|
| Target Name |
HLA-DQA2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3118
|
| Gene ID |
3118 (Homo sapiens)
|
| Target Alternative Names |
HLA-DQA2,DQA1,HLA-DCA,HLA-DXA,HLADQA2,DC-alpha,DX-ALPHA
|
| Uniprot Accession |
P01906
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Phagosome, Cell adhesion molecules, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis
|
| Gene Ensembl |
ENSG00000237541
|
| Target Classification |
|
HLA-DQA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3118 | Pre-made Human HLA-DQA2/DQA1/HLA-DCA siRNA oligo Duplex | 3118 | Human | In-vitro grade; in-vivo grade | Detail |
HLA-DQA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0585-Ab | Human | Anti-Human HLA-DQA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
HLA-DQA2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0585-Ag | Human | Human HLA-DQA2 VLP (virus-like particle) | HEK293 | Products Developing |
