Explore HFE gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. [provided by RefSeq, May 2022]
| Target ID |
GM-MP0577
|
| Target Name |
HFE
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3077
|
| Gene ID |
100053350 (Equus caballus), 100688951 (Canis lupus familiaris), 101084960 (Felis catus), 15216 (Mus musculus)
29199 (Rattus norvegicus), 3077 (Homo sapiens), 497622 (Bos taurus), 696129 (Macaca mulatta)
|
| Target Alternative Names |
HFE,HFE1,HH,HLA-H,Hereditary hemochromatosis protein,Hfe,MR2,MVCD7,TFQTL2
|
| Uniprot Accession |
P70387,O35799,Q30201
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000024981, ENSCAFG00845025572, ENSMUSG00000006611, ENSG00000010704, ENSBTAG00000013065, ENSMMUG00000023733
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of HFE cDNA Clones/ORF Plasmid
HFE siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3077 | Pre-made Human HFE/HH/HFE1 siRNA oligo Duplex | 3077 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29199 | Pre-made Rat Hfe siRNA oligo Duplex | 29199 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15216 | Pre-made Mouse Hfe/MR2 siRNA oligo Duplex | 15216 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696129 | Pre-made Cynomolgus/Rhesus macaque HFE siRNA oligo Duplex | 696129 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084960 | Pre-made Cat/Feline HFE siRNA oligo Duplex | 101084960 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100688951 | Pre-made Dog/Canine HFE siRNA oligo Duplex | 100688951 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497622 | Pre-made Bovines/Cattle HFE siRNA oligo Duplex | 497622 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053350 | Pre-made Equine/Horse HFE siRNA oligo Duplex | 100053350 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HFE antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0577-Ab | Human | Anti-Human HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0577-Ab | Rat | Anti-Rat HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0577-Ab | Mouse | Anti-Mouse HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0577-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0577-Ab | Cat/Feline | Anti-Cat/Feline HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0577-Ab | Dog/Canine | Anti-Dog/Canine HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0577-Ab | Bovines/Cattle | Anti-Bovines/Cattle HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0577-Ab | Equine/Horse | Anti-Equine/Horse HFE monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
HFE VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0577-Ag | Human | Human HFE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0577-Ag | Rat | Rat HFE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0577-Ag | Mouse | Mouse HFE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0577-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HFE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0577-Ag | Cat/Feline | Cat/Feline HFE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0577-Ag | Dog/Canine | Dog/Canine HFE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0577-Ag | Bovines/Cattle | Bovines/Cattle HFE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0577-Ag | Equine/Horse | Equine/Horse HFE VLP (virus-like particle) | HEK293 | Products Developing |
