Explore HAVCR1/CD365 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. The protein is a receptor for multiple other viruses, including Ebola virus, Marburg virus, Dengue virus, and Zika virus and is a possible entry factor for SARS-CoV-2 and other coronaviruses. [provided by RefSeq, Sep 2021]
| Target ID |
GM-MP0572
|
| Target Name |
HAVCR1/CD365
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
26762
|
| Gene ID |
101099778 (Felis catus), 26762 (Homo sapiens), 612069 (Canis lupus familiaris), 715333 (Macaca mulatta)
|
| Target Alternative Names |
CD365,HAVCR,HAVCR-1,HAVCR1,HAVcr-1,Hepatitis A virus cellular receptor 1,KIM-1,KIM1,Kidney injury molecule 1 (KIM-1),T-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1),T-cell immunoglobulin mucin receptor 1 (TIM,T-cell membrane protein 1,TIM,TIM-1,TIM-1),TIM1,TIMD-1,TIMD1
|
| Uniprot Accession |
Q96D42
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Renal fibrosis, Sickle Cell Nephropathy, Type 1 diabetes mellitus with diabetic nephropathy, Type 2 diabetes mellitus, Vasculitis, Vesicoureteral reflux, Acute kidney failure, Autosomal Dominant Polycystic Kidney Disease, Complications of kidney transplant, Congenital hydronephrosis, Cystic fibrosis with pulmonary manifestations, Injury to Kidney, Intraoperative Renal Injury, Kidney disease, Neonatal urinary tract infection, Nephropathy induced by heavy metals, Proteinuria, Renal cell carcinoma, Hydronephrosis, Coronary artery disease, Nephrotic syndrome with diffuse membranous glomerulonephritis
|
| Gene Ensembl |
ENSG00000113249, ENSCAFG00845002501
|
Pre-made viral vector of HAVCR1/CD365 cDNA Clones/ORF Plasmid
HAVCR1/CD365 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo26762 | Pre-made Human HAVCR1/TIM/KIM1 siRNA oligo Duplex | 26762 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715333 | Pre-made Cynomolgus/Rhesus macaque HAVCR1/TIM1 siRNA oligo Duplex | 715333 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099778 | Pre-made Cat/Feline HAVCR1/KIM-1/TIM-1 siRNA oligo Duplex | 101099778 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612069 | Pre-made Dog/Canine HAVCR1 siRNA oligo Duplex | 612069 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
HAVCR1/CD365 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0572-Ab | Human | Anti-Human HAVCR1/CD365 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0572-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HAVCR1/CD365 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0572-Ab | Cat/Feline | Anti-Cat/Feline HAVCR1/CD365 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0572-Ab | Dog/Canine | Anti-Dog/Canine HAVCR1/CD365 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
HAVCR1/CD365 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0572-Ag | Human | Human HAVCR1/CD365 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0572-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HAVCR1/CD365 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0572-Ag | Cat/Feline | Cat/Feline HAVCR1/CD365 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0572-Ag | Dog/Canine | Dog/Canine HAVCR1/CD365 VLP (virus-like particle) | HEK293 | Products Developing |