Explore GFRA2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
| Target ID |
GM-MP0479
|
| Target Name |
GFRA2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2675
|
| Gene ID |
100146260 (Equus caballus), 101091865 (Felis catus), 14586 (Mus musculus), 25136 (Rattus norvegicus)
2675 (Homo sapiens), 514036 (Bos taurus), 609172 (Canis lupus familiaris), 715110 (Macaca mulatta)
|
| Target Alternative Names |
GFRA2,Gfra2,Retl2,NTNRA,RETL2,TRNR2,GDNFRB,NRTNR-ALPHA
|
| Uniprot Accession |
O08842,O00451,Q5E9X0
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000020585, ENSMUSG00000022103, ENSG00000168546, ENSBTAG00000020665, ENSCAFG00845028779, ENSMMUG00000023361
|
| Target Classification |
|
Pre-made viral vector of GFRA2 cDNA Clones/ORF Plasmid
GFRA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2675 | Pre-made Human GFRA2/NTNRA/RETL2 siRNA oligo Duplex | 2675 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25136 | Pre-made Rat Gfra2/Retl2 siRNA oligo Duplex | 25136 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14586 | Pre-made Mouse Gfra2 siRNA oligo Duplex | 14586 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715110 | Pre-made Cynomolgus/Rhesus macaque GFRA2 siRNA oligo Duplex | 715110 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091865 | Pre-made Cat/Feline GFRA2 siRNA oligo Duplex | 101091865 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609172 | Pre-made Dog/Canine GFRA2 siRNA oligo Duplex | 609172 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514036 | Pre-made Bovines/Cattle GFRA2 siRNA oligo Duplex | 514036 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146260 | Pre-made Equine/Horse GFRA2 siRNA oligo Duplex | 100146260 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GFRA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0479-Ab | Human | Anti-Human GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0479-Ab | Rat | Anti-Rat GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0479-Ab | Mouse | Anti-Mouse GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0479-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0479-Ab | Cat/Feline | Anti-Cat/Feline GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0479-Ab | Dog/Canine | Anti-Dog/Canine GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0479-Ab | Bovines/Cattle | Anti-Bovines/Cattle GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0479-Ab | Equine/Horse | Anti-Equine/Horse GFRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GFRA2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0479-Ag | Human | Human GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0479-Ag | Rat | Rat GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0479-Ag | Mouse | Mouse GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0479-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0479-Ag | Cat/Feline | Cat/Feline GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0479-Ag | Dog/Canine | Dog/Canine GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0479-Ag | Bovines/Cattle | Bovines/Cattle GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0479-Ag | Equine/Horse | Equine/Horse GFRA2 VLP (virus-like particle) | HEK293 | Products Developing |
