Explore GABRB3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]
| Target ID |
GM-MP0471
|
| Target Name |
GABRB3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2562
|
| Gene ID |
100050803 (Equus caballus), 100286790 (Felis catus), 14402 (Mus musculus), 24922 (Rattus norvegicus)
2562 (Homo sapiens), 529593 (Bos taurus), 606913 (Canis lupus familiaris), 711754 (Macaca mulatta)
|
| Target Alternative Names |
A230092K12Rik,Cp1,DEE43,ECA5,EIEE43,GABA(A) receptor subunit beta-3 (GABAAR subunit beta-3),GABRB3,Gabrb-3,Gabrb3,Gamma-aminobutyric acid receptor subunit beta-3,beta3
|
| Uniprot Accession |
P63080,P63079,P28472
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Autism, Autistic disorder
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction
|
| Gene Ensembl |
ENSECAG00000022463, ENSMUSG00000033676, ENSG00000166206, ENSBTAG00000013422, ENSCAFG00845018027, ENSMMUG00000051793
|
Pre-made viral vector of GABRB3 cDNA Clones/ORF Plasmid
GABRB3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2562 | Pre-made Human GABRB3/ECA5/DEE43 siRNA oligo Duplex | 2562 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24922 | Pre-made Rat Gabrb3 siRNA oligo Duplex | 24922 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14402 | Pre-made Mouse Gabrb3/Cp1/beta3 siRNA oligo Duplex | 14402 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711754 | Pre-made Cynomolgus/Rhesus macaque GABRB3 siRNA oligo Duplex | 711754 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100286790 | Pre-made Cat/Feline GABRB3 siRNA oligo Duplex | 100286790 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo606913 | Pre-made Dog/Canine GABRB3 siRNA oligo Duplex | 606913 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529593 | Pre-made Bovines/Cattle GABRB3 siRNA oligo Duplex | 529593 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050803 | Pre-made Equine/Horse GABRB3 siRNA oligo Duplex | 100050803 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABRB3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0471-Ab | Human | Anti-Human GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0471-Ab | Rat | Anti-Rat GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0471-Ab | Mouse | Anti-Mouse GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0471-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0471-Ab | Cat/Feline | Anti-Cat/Feline GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0471-Ab | Dog/Canine | Anti-Dog/Canine GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0471-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0471-Ab | Equine/Horse | Anti-Equine/Horse GABRB3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GABRB3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0471-Ag | Human | Human GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0471-Ag | Rat | Rat GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0471-Ag | Mouse | Mouse GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0471-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0471-Ag | Cat/Feline | Cat/Feline GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0471-Ag | Dog/Canine | Dog/Canine GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0471-Ag | Bovines/Cattle | Bovines/Cattle GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0471-Ag | Equine/Horse | Equine/Horse GABRB3 VLP (virus-like particle) | HEK293 | Products Developing |
