Explore Frizzled 8/FZD8 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0466
|
| Target Name |
Frizzled 8/FZD8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8325
|
| Gene ID |
101101229 (Felis catus), 111771171 (Equus caballus), 14370 (Mus musculus), 364754 (Rattus norvegicus)
487073 (Canis lupus familiaris), 616913 (Bos taurus), 708368 (Macaca mulatta), 8325 (Homo sapiens)
|
| Target Alternative Names |
FZ-8,FZD8,Frizzled 8,Frizzled-8,Fz-8,Fz8,Fzd8,hFZ8,hFz8
|
| Uniprot Accession |
Q61091,Q498S8,Q9H461
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Melanogenesis, Cushing syndrome, Alzheimer disease, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma, Breast cancer, Hepatocellular carcinoma, Gastric cancer
|
| Gene Ensembl |
ENSMUSG00000036904, ENSCAFG00845001355, ENSBTAG00000052989, ENSMMUG00000001694, ENSG00000177283
|
Frizzled 8/FZD8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8325 | Pre-made Human FZD8/FZ-8/hFZ8 siRNA oligo Duplex | 8325 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo364754 | Pre-made Rat Fzd8 siRNA oligo Duplex | 364754 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14370 | Pre-made Mouse Fzd8/Fz8 siRNA oligo Duplex | 14370 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708368 | Pre-made Cynomolgus/Rhesus macaque FZD8 siRNA oligo Duplex | 708368 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101229 | Pre-made Cat/Feline FZD8 siRNA oligo Duplex | 101101229 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487073 | Pre-made Dog/Canine FZD8 siRNA oligo Duplex | 487073 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616913 | Pre-made Bovines/Cattle FZD8 siRNA oligo Duplex | 616913 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111771171 | Pre-made Equine/Horse FZD8 siRNA oligo Duplex | 111771171 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Frizzled 8/FZD8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0466-Ab | Human | Anti-Human Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0466-Ab | Rat | Anti-Rat Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0466-Ab | Mouse | Anti-Mouse Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0466-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0466-Ab | Cat/Feline | Anti-Cat/Feline Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0466-Ab | Dog/Canine | Anti-Dog/Canine Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0466-Ab | Bovines/Cattle | Anti-Bovines/Cattle Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0466-Ab | Equine/Horse | Anti-Equine/Horse Frizzled 8/FZD8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
Frizzled 8/FZD8 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0466-Ag | Human | Human Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0466-Ag | Rat | Rat Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0466-Ag | Mouse | Mouse Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0466-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0466-Ag | Cat/Feline | Cat/Feline Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0466-Ag | Dog/Canine | Dog/Canine Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0466-Ag | Bovines/Cattle | Bovines/Cattle Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0466-Ag | Equine/Horse | Equine/Horse Frizzled 8/FZD8 VLP (virus-like particle) | HEK293 | Products Developing |
