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Target
sublocation: Transmembrane Protein.
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Jun 2012]
| Target ID |
GM-MP0422
|
| Target Name |
ERVFRD-1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
405754
|
| Gene ID |
100425316 (Macaca mulatta), 405754 (Homo sapiens)
|
| Target Alternative Names |
ERVFRD-1,envFRD,UNQ6191,ERVFRDE1,GLLL6191,HERV-FRD,HERV-W/FRD
|
| Uniprot Accession |
P60508
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSMMUG00000043161, ENSG00000244476
|
| Target Classification |
|
ERVFRD-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo405754 | Pre-made Human ERVFRD-1/envFRD/UNQ6191 siRNA oligo Duplex | 405754 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100425316 | Pre-made Cynomolgus/Rhesus macaque ERVFRD-1 siRNA oligo Duplex | 100425316 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
ERVFRD-1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0422-Ab | Human | Anti-Human ERVFRD-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0422-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ERVFRD-1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ERVFRD-1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0422-Ag | Human | Human ERVFRD-1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0422-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ERVFRD-1 VLP (virus-like particle) | HEK293 | Products Developing |
