Explore ENPP1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0409
|
| Target Name |
ENPP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5167
|
| Gene ID |
100073097 (Equus caballus), 100856150 (Canis lupus familiaris), 101094350 (Felis catus), 18605 (Mus musculus)
5167 (Homo sapiens), 615535 (Bos taurus), 710140 (Macaca mulatta), 85496 (Rattus norvegicus)
|
| Target Alternative Names |
4833416E15Rik,ARHR2,Alkaline phosphodiesterase I,CD203c,COLED,E-NPP 1,E-NPP1,ENPP1,Ectonucleotide pyrophosphatase/phosphodiesterase family member 1,Enpp1,Ly-41,M6S1,Membrane component chromosome 6 surface marker 1,NPP1,NPPS,Npps,Nucleotide diphosphatase,Nucleotide pyrophosphatase (NPPase),PC-1,PCA1,PDNP1,Pc1,Pca,Pca-1,Pdnp1,Phosphodiesterase I/nucleotide pyrophosphatase 1,Plasma-cell membrane glycoprotein PC-1,ttw,twy
|
| Uniprot Accession |
P06802,P22413,Q924C3
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000013035, ENSCAFG00845000008, ENSMUSG00000037370, ENSG00000197594, ENSBTAG00000021830, ENSMMUG00000014151
|
Pre-made viral vector of ENPP1 cDNA Clones/ORF Plasmid
ENPP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5167 | Pre-made Human ENPP1/M6S1/NPP1 siRNA oligo Duplex | 5167 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo85496 | Pre-made Rat Enpp1/Pc1/Npps siRNA oligo Duplex | 85496 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18605 | Pre-made Mouse Enpp1/Pca/ttw siRNA oligo Duplex | 18605 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710140 | Pre-made Cynomolgus/Rhesus macaque ENPP1 siRNA oligo Duplex | 710140 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094350 | Pre-made Cat/Feline ENPP1 siRNA oligo Duplex | 101094350 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856150 | Pre-made Dog/Canine ENPP1 siRNA oligo Duplex | 100856150 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615535 | Pre-made Bovines/Cattle ENPP1 siRNA oligo Duplex | 615535 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073097 | Pre-made Equine/Horse ENPP1 siRNA oligo Duplex | 100073097 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ENPP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0409-Ab | Human | Anti-Human ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0409-Ab | Rat | Anti-Rat ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0409-Ab | Mouse | Anti-Mouse ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0409-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0409-Ab | Cat/Feline | Anti-Cat/Feline ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0409-Ab | Dog/Canine | Anti-Dog/Canine ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0409-Ab | Bovines/Cattle | Anti-Bovines/Cattle ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0409-Ab | Equine/Horse | Anti-Equine/Horse ENPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ENPP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0409-Ag | Human | Human ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0409-Ag | Rat | Rat ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0409-Ag | Mouse | Mouse ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0409-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0409-Ag | Cat/Feline | Cat/Feline ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0409-Ag | Dog/Canine | Dog/Canine ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0409-Ag | Bovines/Cattle | Bovines/Cattle ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0409-Ag | Equine/Horse | Equine/Horse ENPP1 VLP (virus-like particle) | HEK293 | Products Developing |
