Explore EDAR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0391
|
| Target Name |
EDAR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10913
|
| Gene ID |
100060614 (Equus caballus), 101096644 (Felis catus), 10913 (Homo sapiens), 13608 (Mus musculus)
365581 (Rattus norvegicus), 481305 (Canis lupus familiaris), 613947 (Bos taurus), 695059 (Macaca mulatta)
|
| Target Alternative Names |
EDAR,Edar,DL,ED3,ED5,ED1R,EDA3,HRM1,EDA1R,ECTD10A,ECTD10B,EDA-A1R,dl,RGD1561714
|
| Uniprot Accession |
Q9UNE0,Q9R187
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway
|
| Gene Ensembl |
ENSECAG00000020232, ENSG00000135960, ENSMUSG00000003227, ENSCAFG00845007129, ENSBTAG00000019628, ENSMMUG00000019574
|
| Target Classification |
|
Pre-made viral vector of EDAR cDNA Clones/ORF Plasmid
EDAR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10913 | Pre-made Human EDAR/DL/ED3 siRNA oligo Duplex | 10913 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo365581 | Pre-made Rat Edar/RGD1561714 siRNA oligo Duplex | 365581 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13608 | Pre-made Mouse Edar/dl/ED3 siRNA oligo Duplex | 13608 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695059 | Pre-made Cynomolgus/Rhesus macaque EDAR siRNA oligo Duplex | 695059 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096644 | Pre-made Cat/Feline EDAR siRNA oligo Duplex | 101096644 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481305 | Pre-made Dog/Canine EDAR siRNA oligo Duplex | 481305 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613947 | Pre-made Bovines/Cattle EDAR siRNA oligo Duplex | 613947 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060614 | Pre-made Equine/Horse EDAR siRNA oligo Duplex | 100060614 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EDAR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0391-Ab | Human | Anti-Human EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0391-Ab | Rat | Anti-Rat EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0391-Ab | Mouse | Anti-Mouse EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0391-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0391-Ab | Cat/Feline | Anti-Cat/Feline EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0391-Ab | Dog/Canine | Anti-Dog/Canine EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0391-Ab | Bovines/Cattle | Anti-Bovines/Cattle EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0391-Ab | Equine/Horse | Anti-Equine/Horse EDAR monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
EDAR VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0391-Ag | Human | Human EDAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0391-Ag | Rat | Rat EDAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0391-Ag | Mouse | Mouse EDAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0391-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EDAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0391-Ag | Cat/Feline | Cat/Feline EDAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0391-Ag | Dog/Canine | Dog/Canine EDAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0391-Ag | Bovines/Cattle | Bovines/Cattle EDAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0391-Ag | Equine/Horse | Equine/Horse EDAR VLP (virus-like particle) | HEK293 | Products Developing |
