Explore DSG2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]
| Target ID |
GM-MP0379
|
| Target Name |
DSG2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1829
|
| Gene ID |
100066038 (Equus caballus), 101088118 (Felis catus), 13511 (Mus musculus), 1829 (Homo sapiens)
307562 (Rattus norvegicus), 490500 (Canis lupus familiaris), 508151 (Bos taurus), 705805 (Macaca mulatta)
|
| Target Alternative Names |
CDHF5,Cadherin family member 5,D18Ertd293e,DSG2,Desmoglein-2,Dsg2,HDGC
|
| Uniprot Accession |
O55111,Q14126
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Prostate Cancer, Heart failure, Mucocutaneous lymph node syndrome [Kawasaki]
|
| Disease from KEGG |
Arrhythmogenic right ventricular cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000013616, ENSMUSG00000044393, ENSG00000046604, ENSCAFG00845010678, ENSBTAG00000021923, ENSMMUG00000021095
|
Pre-made viral vector of DSG2 cDNA Clones/ORF Plasmid
DSG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1829 | Pre-made Human DSG2/HDGC/CDHF5 siRNA oligo Duplex | 1829 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo307562 | Pre-made Rat Dsg2 siRNA oligo Duplex | 307562 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13511 | Pre-made Mouse Dsg2/D18Ertd293e siRNA oligo Duplex | 13511 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705805 | Pre-made Cynomolgus/Rhesus macaque DSG2 siRNA oligo Duplex | 705805 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088118 | Pre-made Cat/Feline DSG2 siRNA oligo Duplex | 101088118 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490500 | Pre-made Dog/Canine DSG2 siRNA oligo Duplex | 490500 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508151 | Pre-made Bovines/Cattle DSG2 siRNA oligo Duplex | 508151 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066038 | Pre-made Equine/Horse DSG2 siRNA oligo Duplex | 100066038 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DSG2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0379-Ab | Human | Anti-Human DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0379-Ab | Rat | Anti-Rat DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0379-Ab | Mouse | Anti-Mouse DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0379-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0379-Ab | Cat/Feline | Anti-Cat/Feline DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0379-Ab | Dog/Canine | Anti-Dog/Canine DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0379-Ab | Bovines/Cattle | Anti-Bovines/Cattle DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0379-Ab | Equine/Horse | Anti-Equine/Horse DSG2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
DSG2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0379-Ag | Human | Human DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0379-Ag | Rat | Rat DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0379-Ag | Mouse | Mouse DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0379-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0379-Ag | Cat/Feline | Cat/Feline DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0379-Ag | Dog/Canine | Dog/Canine DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0379-Ag | Bovines/Cattle | Bovines/Cattle DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0379-Ag | Equine/Horse | Equine/Horse DSG2 VLP (virus-like particle) | HEK293 | Products Developing |
