Explore DSG1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
| Target ID |
GM-MP0378
|
| Target Name |
DSG1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1828
|
| Gene ID |
100052088 (Equus caballus), 101085410 (Felis catus), 1828 (Homo sapiens), 281131 (Bos taurus)
291755 (Rattus norvegicus), 403401 (Canis lupus familiaris), 705452 (Macaca mulatta)
|
| Target Alternative Names |
DSG1,Dsg1,DG1,DSG,CDHF4,EPKHE,PPKS1,SPPK1,EPKHIA,Dsg1b,Dsg1c,DSG-1
|
| Uniprot Accession |
Q02413,Q03763,Q9GKQ8
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Staphylococcus aureus infection
|
| Gene Ensembl |
ENSECAG00000018040, ENSG00000134760, ENSBTAG00000013831, ENSCAFG00845011100, ENSMMUG00000022703
|
| Target Classification |
|
DSG1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1828 | Pre-made Human DSG1/DG1/DSG siRNA oligo Duplex | 1828 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo291755 | Pre-made Rat Dsg1/Dsg1b/Dsg1c siRNA oligo Duplex | 291755 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705452 | Pre-made Cynomolgus/Rhesus macaque DSG1 siRNA oligo Duplex | 705452 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085410 | Pre-made Cat/Feline DSG1 siRNA oligo Duplex | 101085410 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403401 | Pre-made Dog/Canine DSG1/DSG-1 siRNA oligo Duplex | 403401 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281131 | Pre-made Bovines/Cattle DSG1 siRNA oligo Duplex | 281131 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052088 | Pre-made Equine/Horse DSG1 siRNA oligo Duplex | 100052088 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DSG1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0378-Ab | Human | Anti-Human DSG1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0378-Ab | Rat | Anti-Rat DSG1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0378-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DSG1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0378-Ab | Cat/Feline | Anti-Cat/Feline DSG1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0378-Ab | Dog/Canine | Anti-Dog/Canine DSG1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0378-Ab | Bovines/Cattle | Anti-Bovines/Cattle DSG1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0378-Ab | Equine/Horse | Anti-Equine/Horse DSG1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
DSG1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0378-Ag | Human | Human DSG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0378-Ag | Rat | Rat DSG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0378-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DSG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0378-Ag | Cat/Feline | Cat/Feline DSG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0378-Ag | Dog/Canine | Dog/Canine DSG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0378-Ag | Bovines/Cattle | Bovines/Cattle DSG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0378-Ag | Equine/Horse | Equine/Horse DSG1 VLP (virus-like particle) | HEK293 | Products Developing |
