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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015]
| Target ID |
GM-MP0373
|
| Target Name |
DSC1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1823
|
| Gene ID |
100065884 (Equus caballus), 101083463 (Felis catus), 13505 (Mus musculus), 1823 (Homo sapiens)
281127 (Bos taurus), 291759 (Rattus norvegicus), 490501 (Canis lupus familiaris), 705332 (Macaca mulatta)
|
| Target Alternative Names |
DSC1,Dsc1,1110020A10Rik,CDHF1,DG2/DG3,dg3,DG2DG3,DSC1b
|
| Uniprot Accession |
P55849,Q08554,Q01107
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000013809, ENSMUSG00000044322, ENSG00000134765, ENSBTAG00000019876, ENSCAFG00845011207, ENSMMUG00000011690
|
| Target Classification |
|
DSC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1823 | Pre-made Human DSC1/CDHF1/DG2/DG3 siRNA oligo Duplex | 1823 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo291759 | Pre-made Rat Dsc1 siRNA oligo Duplex | 291759 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13505 | Pre-made Mouse Dsc1/1110020A10Rik siRNA oligo Duplex | 13505 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705332 | Pre-made Cynomolgus/Rhesus macaque DSC1 siRNA oligo Duplex | 705332 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083463 | Pre-made Cat/Feline DSC1 siRNA oligo Duplex | 101083463 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490501 | Pre-made Dog/Canine DSC1/DSC1b siRNA oligo Duplex | 490501 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281127 | Pre-made Bovines/Cattle DSC1/dg3/DG2DG3 siRNA oligo Duplex | 281127 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065884 | Pre-made Equine/Horse DSC1 siRNA oligo Duplex | 100065884 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DSC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0373-Ab | Human | Anti-Human DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0373-Ab | Rat | Anti-Rat DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0373-Ab | Mouse | Anti-Mouse DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0373-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0373-Ab | Cat/Feline | Anti-Cat/Feline DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0373-Ab | Dog/Canine | Anti-Dog/Canine DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0373-Ab | Bovines/Cattle | Anti-Bovines/Cattle DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0373-Ab | Equine/Horse | Anti-Equine/Horse DSC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
DSC1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0373-Ag | Human | Human DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0373-Ag | Rat | Rat DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0373-Ag | Mouse | Mouse DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0373-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0373-Ag | Cat/Feline | Cat/Feline DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0373-Ag | Dog/Canine | Dog/Canine DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0373-Ag | Bovines/Cattle | Bovines/Cattle DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0373-Ag | Equine/Horse | Equine/Horse DSC1 VLP (virus-like particle) | HEK293 | Products Developing |
