DMPK Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore DMPK gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2016]

Target ID GM-MP0363
Target Name DMPK
Gene Group ldentifer
(Target Gene ID in Homo species)
1760
Gene ID 100146609 (Equus caballus), 101081940 (Felis catus), 13400 (Mus musculus), 1760 (Homo sapiens)
308405 (Rattus norvegicus), 484436 (Canis lupus familiaris), 513675 (Bos taurus), 715328 (Macaca mulatta)
Target Alternative Names DMPK,Dmpk,DM,DMK,Dm15,MDPK,MT-PK,DM1,DM1PK
Uniprot Accession P54265,Q09013
Uniprot Entry Name
Protein Sub-location Transmembrane Protein
Category
Disease cancer, Prostate Cancer
Disease from KEGG
Gene Ensembl ENSECAG00000016750, ENSMUSG00000030409, ENSG00000104936, ENSCAFG00845004793, ENSBTAG00000013347, ENSMMUG00000016457
Target Classification Kinase


DMPK siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo1760Pre-made Human DMPK/DM/DM1 siRNA oligo Duplex1760HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo308405Pre-made Rat Dmpk/Dm15 siRNA oligo Duplex308405RatIn-vitro grade; in-vivo gradeDetail
pGMoligo13400Pre-made Mouse Dmpk/DM/DMK siRNA oligo Duplex13400MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo715328Pre-made Cynomolgus/Rhesus macaque DMPK siRNA oligo Duplex715328Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101081940Pre-made Cat/Feline DMPK siRNA oligo Duplex101081940Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo484436Pre-made Dog/Canine DMPK siRNA oligo Duplex484436Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo513675Pre-made Bovines/Cattle DMPK siRNA oligo Duplex513675Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100146609Pre-made Equine/Horse DMPK siRNA oligo Duplex100146609Equine/HorseIn-vitro grade; in-vivo gradeDetail


DMPK antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-MP0363-AbHumanAnti-Human DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-rg-MP0363-AbRatAnti-Rat DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-mg-MP0363-AbMouseAnti-Mouse DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cynog-MP0363-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-felg-MP0363-AbCat/FelineAnti-Cat/Feline DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cang-MP0363-AbDog/CanineAnti-Dog/Canine DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-bovg-MP0363-AbBovines/CattleAnti-Bovines/Cattle DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-equg-MP0363-AbEquine/HorseAnti-Equine/Horse DMPK monoclonal antibodymabFACS/Biofunctional AntibodyDetail


DMPK VLP (virus-like particle)

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-MP0363-AgHumanHuman DMPK VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-MP0363-AgRatRat DMPK VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-MP0363-AgMouseMouse DMPK VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-MP0363-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque DMPK VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-MP0363-AgCat/FelineCat/Feline DMPK VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-MP0363-AgDog/CanineDog/Canine DMPK VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-MP0363-AgBovines/CattleBovines/Cattle DMPK VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-MP0363-AgEquine/HorseEquine/Horse DMPK VLP (virus-like particle)HEK293Products Developing