Explore CRB1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012]
| Target ID |
GM-MP0331
|
| Target Name |
CRB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23418
|
| Gene ID |
100061068 (Equus caballus), 101092328 (Felis catus), 170788 (Mus musculus), 23418 (Homo sapiens)
304825 (Rattus norvegicus), 490260 (Canis lupus familiaris), 520406 (Bos taurus), 710991 (Macaca mulatta)
|
| Target Alternative Names |
7530426H14Rik,A930008G09Rik,CRB1,CRB1-A,CRB1-A2,CRB1-B,CRB1-C,Crb1,LCA8,Protein crumbs homolog 1,RP12
|
| Uniprot Accession |
Q8VHS2,P82279
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Hippo signaling pathway
|
| Gene Ensembl |
ENSECAG00000010669, ENSMUSG00000063681, ENSG00000134376, ENSCAFG00845000998, ENSBTAG00000008944, ENSMMUG00000012322
|
CRB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23418 | Pre-made Human CRB1/LCA8/RP12 siRNA oligo Duplex | 23418 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo304825 | Pre-made Rat Crb1 siRNA oligo Duplex | 304825 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170788 | Pre-made Mouse Crb1/CRB1-A/CRB1-B siRNA oligo Duplex | 170788 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710991 | Pre-made Cynomolgus/Rhesus macaque CRB1 siRNA oligo Duplex | 710991 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092328 | Pre-made Cat/Feline CRB1 siRNA oligo Duplex | 101092328 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490260 | Pre-made Dog/Canine CRB1 siRNA oligo Duplex | 490260 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520406 | Pre-made Bovines/Cattle CRB1 siRNA oligo Duplex | 520406 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061068 | Pre-made Equine/Horse CRB1 siRNA oligo Duplex | 100061068 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CRB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0331-Ab | Human | Anti-Human CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0331-Ab | Rat | Anti-Rat CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0331-Ab | Mouse | Anti-Mouse CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0331-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0331-Ab | Cat/Feline | Anti-Cat/Feline CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0331-Ab | Dog/Canine | Anti-Dog/Canine CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0331-Ab | Bovines/Cattle | Anti-Bovines/Cattle CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0331-Ab | Equine/Horse | Anti-Equine/Horse CRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CRB1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0331-Ag | Human | Human CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0331-Ag | Rat | Rat CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0331-Ag | Mouse | Mouse CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0331-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0331-Ag | Cat/Feline | Cat/Feline CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0331-Ag | Dog/Canine | Dog/Canine CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0331-Ag | Bovines/Cattle | Bovines/Cattle CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0331-Ag | Equine/Horse | Equine/Horse CRB1 VLP (virus-like particle) | HEK293 | Products Developing |
