Explore CLEC7A/Dectin-1/CD369 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0301
|
| Target Name |
CLEC7A/Dectin-1/CD369
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
64581
|
| Gene ID |
100053863 (Equus caballus), 101083523 (Felis catus), 502902 (Rattus norvegicus), 532865 (Bos taurus)
56644 (Mus musculus), 574356 (Macaca mulatta), 611385 (Canis lupus familiaris), 64581 (Homo sapiens)
|
| Target Alternative Names |
BGR,Beta-glucan receptor,C-type lectin domain family 7 member A,C-type lectin superfamily member 12,CANDF4,CD369,CLEC7A,CLECSF12,Clec7a,Clec7b,Clecsf12,DECTIN1,Dectin-1,Dectin-1),Dendritic cell-associated C-type lectin 1 (DC-associated C-type lectin 1,RGD1565140,SCARE2,beta-GR
|
| Uniprot Accession |
Q49BZ4,Q6QLQ4,Q8HZR8,Q9BXN2
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Phagosome, C-type lectin receptor signaling pathway, Tuberculosis
|
| Gene Ensembl |
ENSECAG00000009079, ENSBTAG00000014546, ENSMUSG00000079293, ENSMMUG00000002192, ENSCAFG00845026991, ENSG00000172243
|
Pre-made viral vector of CLEC7A/Dectin-1/CD369 cDNA Clones/ORF Plasmid
CLEC7A/Dectin-1/CD369 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo64581 | Pre-made Human CLEC7A/BGR/CD369 siRNA oligo Duplex | 64581 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo502902 | Pre-made Rat Clec7a/Clec7b/RGD1565140 siRNA oligo Duplex | 502902 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56644 | Pre-made Mouse Clec7a/BGR/beta-GR siRNA oligo Duplex | 56644 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574356 | Pre-made Cynomolgus/Rhesus macaque CLEC7A siRNA oligo Duplex | 574356 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083523 | Pre-made Cat/Feline CLEC7A siRNA oligo Duplex | 101083523 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611385 | Pre-made Dog/Canine CLEC7A siRNA oligo Duplex | 611385 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532865 | Pre-made Bovines/Cattle CLEC7A siRNA oligo Duplex | 532865 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053863 | Pre-made Equine/Horse CLEC7A siRNA oligo Duplex | 100053863 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CLEC7A/Dectin-1/CD369 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0301-Ab | Human | Anti-Human CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0301-Ab | Rat | Anti-Rat CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0301-Ab | Mouse | Anti-Mouse CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0301-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0301-Ab | Cat/Feline | Anti-Cat/Feline CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0301-Ab | Dog/Canine | Anti-Dog/Canine CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0301-Ab | Bovines/Cattle | Anti-Bovines/Cattle CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0301-Ab | Equine/Horse | Anti-Equine/Horse CLEC7A/Dectin-1/CD369 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CLEC7A/Dectin-1/CD369 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0301-Ag | Human | Human CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0301-Ag | Rat | Rat CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0301-Ag | Mouse | Mouse CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0301-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0301-Ag | Cat/Feline | Cat/Feline CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0301-Ag | Dog/Canine | Dog/Canine CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0301-Ag | Bovines/Cattle | Bovines/Cattle CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0301-Ag | Equine/Horse | Equine/Horse CLEC7A/Dectin-1/CD369 VLP (virus-like particle) | HEK293 | Products Developing |
