Explore Claudin 2/CLDN2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
| Target ID |
GM-MP0280
|
| Target Name |
Claudin 2/CLDN2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9075
|
| Gene ID |
100054776 (Equus caballus), 101080691 (Felis catus), 12738 (Mus musculus), 300920 (Rattus norvegicus)
403649 (Canis lupus familiaris), 404089 (Bos taurus), 701378 (Macaca mulatta), 9075 (Homo sapiens)
|
| Target Alternative Names |
CLDN2,Claudin 2,Claudin-2,Cldn2,OAZON,RGD1560247,SP82,claudin-2
|
| Uniprot Accession |
O88552,Q95KM6,Q765P1,P57739
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Hepatitis C
|
| Gene Ensembl |
ENSECAG00000003417, ENSMUSG00000047230, ENSG00000165376
|
Claudin 2/CLDN2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9075 | Pre-made Human CLDN2/OAZON/claudin-2 siRNA oligo Duplex | 9075 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo300920 | Pre-made Rat Cldn2/RGD1560247 siRNA oligo Duplex | 300920 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12738 | Pre-made Mouse Cldn2 siRNA oligo Duplex | 12738 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701378 | Pre-made Cynomolgus/Rhesus macaque CLDN2/SP82 siRNA oligo Duplex | 701378 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080691 | Pre-made Cat/Feline CLDN2 siRNA oligo Duplex | 101080691 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403649 | Pre-made Dog/Canine CLDN2/Claudin-2 siRNA oligo Duplex | 403649 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404089 | Pre-made Bovines/Cattle CLDN2 siRNA oligo Duplex | 404089 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054776 | Pre-made Equine/Horse CLDN2 siRNA oligo Duplex | 100054776 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Claudin 2/CLDN2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0280-Ab | Human | Anti-Human Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0280-Ab | Rat | Anti-Rat Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0280-Ab | Mouse | Anti-Mouse Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0280-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0280-Ab | Cat/Feline | Anti-Cat/Feline Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0280-Ab | Dog/Canine | Anti-Dog/Canine Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0280-Ab | Bovines/Cattle | Anti-Bovines/Cattle Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0280-Ab | Equine/Horse | Anti-Equine/Horse Claudin 2/CLDN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Claudin 2/CLDN2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0280-Ag | Human | Human Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0280-Ag | Rat | Rat Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0280-Ag | Mouse | Mouse Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0280-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0280-Ag | Cat/Feline | Cat/Feline Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0280-Ag | Dog/Canine | Dog/Canine Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0280-Ag | Bovines/Cattle | Bovines/Cattle Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0280-Ag | Equine/Horse | Equine/Horse Claudin 2/CLDN2 VLP (virus-like particle) | HEK293 | Products Developing |
