Explore CLDN12 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011]
| Target ID |
GM-MP0273
|
| Target Name |
CLDN12
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9069
|
| Gene ID |
100060361 (Equus caballus), 101081208 (Felis catus), 500000 (Rattus norvegicus), 538709 (Bos taurus)
608397 (Canis lupus familiaris), 64945 (Mus musculus), 704058 (Macaca mulatta), 9069 (Homo sapiens)
|
| Target Alternative Names |
CLDN12,Claudin-12,Cldn12,RGD1561053,claudin-12
|
| Uniprot Accession |
Q0IIL2,Q9ET43,P56749
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSECAG00000005767, ENSBTAG00000019486, ENSCAFG00845011713, ENSMUSG00000046798, ENSMMUG00000023657, ENSG00000157224
|
Pre-made viral vector of CLDN12 cDNA Clones/ORF Plasmid
CLDN12 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9069 | Pre-made Human CLDN12 siRNA oligo Duplex | 9069 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500000 | Pre-made Rat Cldn12/RGD1561053 siRNA oligo Duplex | 500000 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64945 | Pre-made Mouse Cldn12 siRNA oligo Duplex | 64945 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704058 | Pre-made Cynomolgus/Rhesus macaque CLDN12/claudin-12 siRNA oligo Duplex | 704058 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081208 | Pre-made Cat/Feline CLDN12 siRNA oligo Duplex | 101081208 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608397 | Pre-made Dog/Canine CLDN12 siRNA oligo Duplex | 608397 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538709 | Pre-made Bovines/Cattle CLDN12/claudin-12 siRNA oligo Duplex | 538709 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060361 | Pre-made Equine/Horse CLDN12 siRNA oligo Duplex | 100060361 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CLDN12 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0273-Ab | Human | Anti-Human CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0273-Ab | Rat | Anti-Rat CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0273-Ab | Mouse | Anti-Mouse CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0273-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0273-Ab | Cat/Feline | Anti-Cat/Feline CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0273-Ab | Dog/Canine | Anti-Dog/Canine CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0273-Ab | Bovines/Cattle | Anti-Bovines/Cattle CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0273-Ab | Equine/Horse | Anti-Equine/Horse CLDN12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CLDN12 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0273-Ag | Human | Human CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0273-Ag | Rat | Rat CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0273-Ag | Mouse | Mouse CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0273-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0273-Ag | Cat/Feline | Cat/Feline CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0273-Ag | Dog/Canine | Dog/Canine CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0273-Ag | Bovines/Cattle | Bovines/Cattle CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0273-Ag | Equine/Horse | Equine/Horse CLDN12 VLP (virus-like particle) | HEK293 | Products Developing |
