Explore CHRNG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[provided by RefSeq, Sep 2009]
| Target ID |
GM-MP0265
|
| Target Name |
CHRNG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1146
|
| Gene ID |
100057215 (Equus caballus), 101098733 (Felis catus), 11449 (Mus musculus), 1146 (Homo sapiens)
25753 (Rattus norvegicus), 281689 (Bos taurus), 486163 (Canis lupus familiaris), 713418 (Macaca mulatta)
|
| Target Alternative Names |
ACHRG,Acetylcholine receptor subunit gamma,Achr-3,Acrg,CHRNG,Chrng
|
| Uniprot Accession |
P04760,P07510,P18916,P13536
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000002376, ENSMUSG00000026253, ENSG00000196811, ENSBTAG00000045943, ENSCAFG00845025890, ENSMMUG00000022149
|
CHRNG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1146 | Pre-made Human CHRNG/ACHRG siRNA oligo Duplex | 1146 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25753 | Pre-made Rat Chrng/ACHRG siRNA oligo Duplex | 25753 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11449 | Pre-made Mouse Chrng/Acrg/Achr-3 siRNA oligo Duplex | 11449 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713418 | Pre-made Cynomolgus/Rhesus macaque CHRNG siRNA oligo Duplex | 713418 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098733 | Pre-made Cat/Feline CHRNG siRNA oligo Duplex | 101098733 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486163 | Pre-made Dog/Canine CHRNG siRNA oligo Duplex | 486163 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281689 | Pre-made Bovines/Cattle CHRNG siRNA oligo Duplex | 281689 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057215 | Pre-made Equine/Horse CHRNG siRNA oligo Duplex | 100057215 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CHRNG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0265-Ab | Human | Anti-Human CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0265-Ab | Rat | Anti-Rat CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0265-Ab | Mouse | Anti-Mouse CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0265-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0265-Ab | Cat/Feline | Anti-Cat/Feline CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0265-Ab | Dog/Canine | Anti-Dog/Canine CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0265-Ab | Bovines/Cattle | Anti-Bovines/Cattle CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0265-Ab | Equine/Horse | Anti-Equine/Horse CHRNG monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CHRNG VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0265-Ag | Human | Human CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0265-Ag | Rat | Rat CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0265-Ag | Mouse | Mouse CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0265-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0265-Ag | Cat/Feline | Cat/Feline CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0265-Ag | Dog/Canine | Dog/Canine CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0265-Ag | Bovines/Cattle | Bovines/Cattle CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0265-Ag | Equine/Horse | Equine/Horse CHRNG VLP (virus-like particle) | HEK293 | Products Developing |
