Explore CHRNA3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
| Target ID |
GM-MP0260
|
| Target Name |
CHRNA3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1136
|
| Gene ID |
100037403 (Felis catus), 100060452 (Equus caballus), 110834 (Mus musculus), 1136 (Homo sapiens)
25101 (Rattus norvegicus), 282702 (Bos taurus), 482111 (Canis lupus familiaris), 716571 (Macaca mulatta)
|
| Target Alternative Names |
(a)3,A730007P14Rik,Acra-3,Acra3,BAIPRCK,CHRNA3,Chrna3,LNCR2,NACHRA3,Neuronal acetylcholine receptor subunit alpha-3,PAOD2,nica3
|
| Uniprot Accession |
Q8R4G9,P32297,P04757,Q07263
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor activation
|
| Gene Ensembl |
ENSECAG00000010412, ENSMUSG00000032303, ENSG00000080644, ENSBTAG00000003130, ENSCAFG00845012908, ENSMMUG00000023736
|
CHRNA3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1136 | Pre-made Human CHRNA3/LNCR2/PAOD2 siRNA oligo Duplex | 1136 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25101 | Pre-made Rat Chrna3 siRNA oligo Duplex | 25101 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110834 | Pre-made Mouse Chrna3/(a)3/Acra3 siRNA oligo Duplex | 110834 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716571 | Pre-made Cynomolgus/Rhesus macaque CHRNA3/nica3 siRNA oligo Duplex | 716571 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100037403 | Pre-made Cat/Feline CHRNA3 siRNA oligo Duplex | 100037403 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482111 | Pre-made Dog/Canine CHRNA3 siRNA oligo Duplex | 482111 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282702 | Pre-made Bovines/Cattle CHRNA3 siRNA oligo Duplex | 282702 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060452 | Pre-made Equine/Horse CHRNA3 siRNA oligo Duplex | 100060452 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CHRNA3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0260-Ab | Human | Anti-Human CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0260-Ab | Rat | Anti-Rat CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0260-Ab | Mouse | Anti-Mouse CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0260-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0260-Ab | Cat/Feline | Anti-Cat/Feline CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0260-Ab | Dog/Canine | Anti-Dog/Canine CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0260-Ab | Bovines/Cattle | Anti-Bovines/Cattle CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0260-Ab | Equine/Horse | Anti-Equine/Horse CHRNA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CHRNA3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0260-Ag | Human | Human CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0260-Ag | Rat | Rat CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0260-Ag | Mouse | Mouse CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0260-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0260-Ag | Cat/Feline | Cat/Feline CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0260-Ag | Dog/Canine | Dog/Canine CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0260-Ag | Bovines/Cattle | Bovines/Cattle CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0260-Ag | Equine/Horse | Equine/Horse CHRNA3 VLP (virus-like particle) | HEK293 | Products Developing |
