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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0199
|
| Target Name |
CD1c/CD1C
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
911
|
| Gene ID |
717148 (Macaca mulatta), 911 (Homo sapiens)
|
| Target Alternative Names |
BDCA1,CD1,CD1A,CD1C,CD1c,R7,T-cell surface glycoprotein CD1c
|
| Uniprot Accession |
P29017
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Tight junction, Hematopoietic cell lineage, Amoebiasis
|
| Gene Ensembl |
ENSMMUG00000010626, ENSG00000158481
|
CD1c/CD1C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo911 | Pre-made Human CD1C/R7/CD1 siRNA oligo Duplex | 911 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717148 | Pre-made Cynomolgus/Rhesus macaque CD1C siRNA oligo Duplex | 717148 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CD1c/CD1C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0199-Ab | Human | Anti-Human CD1c/CD1C monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0199-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD1c/CD1C monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD1c/CD1C VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0199-Ag | Human | Human CD1c/CD1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0199-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD1c/CD1C VLP (virus-like particle) | HEK293 | Products Developing |
