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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0198
|
| Target Name |
CD1B/CD1b
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
910
|
| Gene ID |
718955 (Macaca mulatta), 910 (Homo sapiens)
|
| Target Alternative Names |
CD1,CD1A,CD1B,CD1b,R1,T-cell surface glycoprotein CD1b
|
| Uniprot Accession |
P29016
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Tight junction, Hematopoietic cell lineage, Amoebiasis
|
| Gene Ensembl |
ENSMMUG00000016783, ENSG00000158485
|
Pre-made viral vector of CD1B/CD1b cDNA Clones/ORF Plasmid
CD1B/CD1b siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo910 | Pre-made Human CD1B/R1/CD1 siRNA oligo Duplex | 910 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718955 | Pre-made Cynomolgus/Rhesus macaque CD1B siRNA oligo Duplex | 718955 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CD1B/CD1b antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0198-Ab | Human | Anti-Human CD1B/CD1b monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0198-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD1B/CD1b monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD1B/CD1b VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0198-Ag | Human | Human CD1B/CD1b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0198-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD1B/CD1b VLP (virus-like particle) | HEK293 | Products Developing |