Explore CD177 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
| Target ID |
GM-MP0196
|
| Target Name |
CD177
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
57126
|
| Gene ID |
101081848 (Felis catus), 57126 (Homo sapiens), 612424 (Canis lupus familiaris), 616350 (Bos taurus)
711291 (Macaca mulatta)
|
| Target Alternative Names |
CD177,CD177 antigen,HNA-2a,HNA2A,Human neutrophil alloantigen 2a (HNA-2a),NB1,NB1 GP,NB1 glycoprotein (NB1 GP),PRV-1,PRV1,Polycythemia rubra vera protein 1 (PRV-1)
|
| Uniprot Accession |
Q8N6Q3
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSG00000204936, ENSCAFG00845000474, ENSBTAG00000002976
|
| Target Classification |
|
Pre-made viral vector of CD177 cDNA Clones/ORF Plasmid
CD177 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57126 | Pre-made Human CD177/NB1/PRV1 siRNA oligo Duplex | 57126 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711291 | Pre-made Cynomolgus/Rhesus macaque CD177 siRNA oligo Duplex | 711291 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081848 | Pre-made Cat/Feline CD177 siRNA oligo Duplex | 101081848 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612424 | Pre-made Dog/Canine CD177 siRNA oligo Duplex | 612424 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616350 | Pre-made Bovines/Cattle CD177 siRNA oligo Duplex | 616350 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
CD177 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0196-Ab | Human | Anti-Human CD177 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0196-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD177 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0196-Ab | Cat/Feline | Anti-Cat/Feline CD177 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0196-Ab | Dog/Canine | Anti-Dog/Canine CD177 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0196-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD177 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD177 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0196-Ag | Human | Human CD177 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0196-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD177 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0196-Ag | Cat/Feline | Cat/Feline CD177 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0196-Ag | Dog/Canine | Dog/Canine CD177 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0196-Ag | Bovines/Cattle | Bovines/Cattle CD177 VLP (virus-like particle) | HEK293 | Products Developing |
