Explore BTNL2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. [provided by RefSeq, May 2017]
| Target ID |
GM-MP0149
|
| Target Name |
BTNL2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
56244
|
| Gene ID |
100051881 (Equus caballus), 101081631 (Felis catus), 309620 (Rattus norvegicus), 481730 (Canis lupus familiaris)
547431 (Mus musculus), 56244 (Homo sapiens), 789224 (Bos taurus)
|
| Target Alternative Names |
BTNL2,Btnl2,Ng9,BTL-II,NG9,Btl2,BTLN2,Gm315,SS2,BTN7,HSBLMHC1
|
| Uniprot Accession |
Q6MG97,O70355,Q9UIR0
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000011452, ENSCAFG00845017222, ENSMUSG00000024340, ENSG00000204290, ENSBTAG00000034939
|
| Target Classification |
|
BTNL2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo56244 | Pre-made Human BTNL2/SS2/BTN7 siRNA oligo Duplex | 56244 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo309620 | Pre-made Rat Btnl2/Ng9/BTL-II siRNA oligo Duplex | 309620 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo547431 | Pre-made Mouse Btnl2/NG9/Btl2 siRNA oligo Duplex | 547431 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081631 | Pre-made Cat/Feline BTNL2 siRNA oligo Duplex | 101081631 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481730 | Pre-made Dog/Canine BTNL2 siRNA oligo Duplex | 481730 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo789224 | Pre-made Bovines/Cattle BTNL2 siRNA oligo Duplex | 789224 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051881 | Pre-made Equine/Horse BTNL2 siRNA oligo Duplex | 100051881 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BTNL2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0149-Ab | Human | Anti-Human BTNL2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0149-Ab | Rat | Anti-Rat BTNL2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0149-Ab | Mouse | Anti-Mouse BTNL2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0149-Ab | Cat/Feline | Anti-Cat/Feline BTNL2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0149-Ab | Dog/Canine | Anti-Dog/Canine BTNL2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0149-Ab | Bovines/Cattle | Anti-Bovines/Cattle BTNL2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0149-Ab | Equine/Horse | Anti-Equine/Horse BTNL2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
BTNL2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0149-Ag | Human | Human BTNL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0149-Ag | Rat | Rat BTNL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0149-Ag | Mouse | Mouse BTNL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0149-Ag | Cat/Feline | Cat/Feline BTNL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0149-Ag | Dog/Canine | Dog/Canine BTNL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0149-Ag | Bovines/Cattle | Bovines/Cattle BTNL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0149-Ag | Equine/Horse | Equine/Horse BTNL2 VLP (virus-like particle) | HEK293 | Products Developing |
