BMPR1B/CDw293 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore BMPR1B/CDw293 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Target ID GM-MP0137
Target Name BMPR1B/CDw293
Gene Group ldentifer
(Target Gene ID in Homo species)
658
Gene ID 100053554 (Equus caballus), 101082489 (Felis catus), 12167 (Mus musculus), 310914 (Rattus norvegicus)
407128 (Bos taurus), 478484 (Canis lupus familiaris), 658 (Homo sapiens), 705474 (Macaca mulatta)
Target Alternative Names BMPR1B,Bmpr1b,Alk6,SKR6,ALK-6,Acvrlk6,BMPR-1B,BMPR-IB,CFK-43a,ALK6,BMP15,BMPRIB,AMD3,AMDD,BDA2,BDA1D,CDw293
Uniprot Accession P36898,O00238
Uniprot Entry Name
Protein Sub-location Transmembrane Protein
Category Cytokine Target
Disease cancer
Disease from KEGG Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Axon guidance, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Fluid shear stress and atherosclerosis
Gene Ensembl ENSECAG00000012140, ENSMUSG00000052430, ENSBTAG00000002081, ENSCAFG00845021570, ENSG00000138696, ENSMMUG00000006702
Target Classification Cytokine Receptor, Kinase


Pre-made viral vector of BMPR1B/CDw293 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP005278Human BMPR1B/ALK-6/ALK6 Lentivirus plasmidNM_001256792.1658HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005278Human BMPR1B/ALK-6/ALK6 Lentivirus particleNM_001256792.1658HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


BMPR1B/CDw293 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo658Pre-made Human BMPR1B/ALK6/AMD3 siRNA oligo Duplex658HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo310914Pre-made Rat Bmpr1b/CFK-43a siRNA oligo Duplex310914RatIn-vitro grade; in-vivo gradeDetail
pGMoligo12167Pre-made Mouse Bmpr1b/Alk6/SKR6 siRNA oligo Duplex12167MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo705474Pre-made Cynomolgus/Rhesus macaque BMPR1B siRNA oligo Duplex705474Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101082489Pre-made Cat/Feline BMPR1B siRNA oligo Duplex101082489Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo478484Pre-made Dog/Canine BMPR1B siRNA oligo Duplex478484Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo407128Pre-made Bovines/Cattle BMPR1B/ALK6/BMP15 siRNA oligo Duplex407128Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100053554Pre-made Equine/Horse BMPR1B siRNA oligo Duplex100053554Equine/HorseIn-vitro grade; in-vivo gradeDetail


BMPR1B/CDw293 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-MP0137-AbHumanAnti-Human BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-rg-MP0137-AbRatAnti-Rat BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-mg-MP0137-AbMouseAnti-Mouse BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-cynog-MP0137-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-felg-MP0137-AbCat/FelineAnti-Cat/Feline BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-cang-MP0137-AbDog/CanineAnti-Dog/Canine BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-bovg-MP0137-AbBovines/CattleAnti-Bovines/Cattle BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail
GM-Tg-equg-MP0137-AbEquine/HorseAnti-Equine/Horse BMPR1B/CDw293 monoclonal antibodymabFACS/Biofunctional Antibody, Cytokine antibodyDetail


BMPR1B/CDw293 VLP (virus-like particle)

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-MP0137-AgHumanHuman BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-MP0137-AgRatRat BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-MP0137-AgMouseMouse BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-MP0137-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-MP0137-AgCat/FelineCat/Feline BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-MP0137-AgDog/CanineDog/Canine BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-MP0137-AgBovines/CattleBovines/Cattle BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-MP0137-AgEquine/HorseEquine/Horse BMPR1B/CDw293 VLP (virus-like particle)HEK293Products Developing