Explore BMPR1A/CD292 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0136
|
| Target Name |
BMPR1A/CD292
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
657
|
| Gene ID |
100064367 (Equus caballus), 101089548 (Felis catus), 12166 (Mus musculus), 404101 (Bos taurus) 489077 (Canis lupus familiaris), 657 (Homo sapiens), 696898 (Macaca mulatta), 81507 (Rattus norvegicus)
|
| Target Alternative Names |
10q23del,1110037I22Rik,ACVRLK3,ALK-3,ALK3,Activin receptor-like kinase 3 (ALK-3),BMP type-1A receptor,BMPR-1A,BMPR-IA,BMPR1A,Bmpr,Bmpr1a,Bone morphogenetic protein receptor type-1A,CD292,SKR5,Serine/threonine-protein kinase receptor R5 (SKR5)
|
| Uniprot Accession |
P36895,P36894,Q78EA7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000020461, ENSMUSG00000021796, ENSBTAG00000000231, ENSCAFG00845006910, ENSG00000107779, ENSMMUG00000011852
|
| Target Classification |
Cytokine Receptor, Pathway, Tumor-associated antigen (TAA)
|
Pre-made viral vector of BMPR1A/CD292 cDNA Clones/ORF Plasmid
BMPR1A/CD292 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo657 | Pre-made Human BMPR1A/ALK3/SKR5 siRNA oligo Duplex | 657 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81507 | Pre-made Rat Bmpr1a siRNA oligo Duplex | 81507 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12166 | Pre-made Mouse Bmpr1a/ALK3/Bmpr siRNA oligo Duplex | 12166 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696898 | Pre-made Cynomolgus/Rhesus macaque BMPR1A siRNA oligo Duplex | 696898 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089548 | Pre-made Cat/Feline BMPR1A siRNA oligo Duplex | 101089548 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489077 | Pre-made Dog/Canine BMPR1A siRNA oligo Duplex | 489077 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404101 | Pre-made Bovines/Cattle BMPR1A/BMPR-IA siRNA oligo Duplex | 404101 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064367 | Pre-made Equine/Horse BMPR1A siRNA oligo Duplex | 100064367 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMPR1A/CD292 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0136-Ab | Human | Anti-Human BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0136-Ab | Rat | Anti-Rat BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0136-Ab | Mouse | Anti-Mouse BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0136-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0136-Ab | Cat/Feline | Anti-Cat/Feline BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0136-Ab | Dog/Canine | Anti-Dog/Canine BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0136-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0136-Ab | Equine/Horse | Anti-Equine/Horse BMPR1A/CD292 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
BMPR1A/CD292 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0136-Ag | Human | Human BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0136-Ag | Rat | Rat BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0136-Ag | Mouse | Mouse BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0136-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0136-Ag | Cat/Feline | Cat/Feline BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0136-Ag | Dog/Canine | Dog/Canine BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0136-Ag | Bovines/Cattle | Bovines/Cattle BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0136-Ag | Equine/Horse | Equine/Horse BMPR1A/CD292 VLP (virus-like particle) | HEK293 | Products Developing |