Explore ATX3/ATXN3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016]
| Target ID |
GM-MP0127
|
| Target Name |
ATX3/ATXN3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4287
|
| Gene ID |
100053162 (Equus caballus), 101096738 (Felis catus), 110616 (Mus musculus), 4287 (Homo sapiens)
480229 (Canis lupus familiaris), 60331 (Rattus norvegicus), 720515 (Macaca mulatta), 790880 (Bos taurus)
|
| Target Alternative Names |
2210008M02Rik,AT3,ATX3,ATXN3,Ataxin-3,Atxn3,JOS,MJD,MJD1,Machado-Joseph disease protein 1,Mjd,Rsca3,SCA3,Sca3,Spinocerebellar ataxia type 3 protein,ataxin-3
|
| Uniprot Accession |
Q9CVD2,P54252,O35815
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum
|
| Gene Ensembl |
ENSECAG00000015533, ENSMUSG00000021189, ENSG00000066427, ENSCAFG00845020186, ENSMMUG00000020751, ENSBTAG00000005786
|
Pre-made viral vector of ATX3/ATXN3 cDNA Clones/ORF Plasmid
ATX3/ATXN3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4287 | Pre-made Human ATXN3/AT3/JOS siRNA oligo Duplex | 4287 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60331 | Pre-made Rat Atxn3/MJD1/Rsca3 siRNA oligo Duplex | 60331 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110616 | Pre-made Mouse Atxn3/Mjd/ATX3 siRNA oligo Duplex | 110616 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720515 | Pre-made Cynomolgus/Rhesus macaque ATXN3 siRNA oligo Duplex | 720515 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096738 | Pre-made Cat/Feline ATXN3 siRNA oligo Duplex | 101096738 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480229 | Pre-made Dog/Canine ATXN3 siRNA oligo Duplex | 480229 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo790880 | Pre-made Bovines/Cattle ATXN3/ataxin-3 siRNA oligo Duplex | 790880 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053162 | Pre-made Equine/Horse ATXN3 siRNA oligo Duplex | 100053162 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ATX3/ATXN3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0127-Ab | Human | Anti-Human ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0127-Ab | Rat | Anti-Rat ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0127-Ab | Mouse | Anti-Mouse ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0127-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0127-Ab | Cat/Feline | Anti-Cat/Feline ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0127-Ab | Dog/Canine | Anti-Dog/Canine ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0127-Ab | Bovines/Cattle | Anti-Bovines/Cattle ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0127-Ab | Equine/Horse | Anti-Equine/Horse ATX3/ATXN3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ATX3/ATXN3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0127-Ag | Human | Human ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0127-Ag | Rat | Rat ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0127-Ag | Mouse | Mouse ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0127-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0127-Ag | Cat/Feline | Cat/Feline ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0127-Ag | Dog/Canine | Dog/Canine ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0127-Ag | Bovines/Cattle | Bovines/Cattle ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0127-Ag | Equine/Horse | Equine/Horse ATX3/ATXN3 VLP (virus-like particle) | HEK293 | Products Developing |
