Explore ATP7A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013]
| Target ID |
GM-MP0116
|
| Target Name |
ATP7A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
538
|
| Gene ID |
100071762 (Equus caballus), 101086954 (Felis catus), 11977 (Mus musculus), 24941 (Rattus norvegicus)
406185 (Canis lupus familiaris), 538 (Homo sapiens), 541275 (Bos taurus), 705857 (Macaca mulatta)
|
| Target Alternative Names |
ATP7A,Atp7a,Copper pump 1,Copper-transporting ATPase 1,DSMAX,HMNX,MK,MNK,Menkes disease-associated protein,Mnk,SMAX3
|
| Uniprot Accession |
Q64430,P70705,Q04656
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Mineral absorption
|
| Gene Ensembl |
ENSECAG00000016767, ENSMUSG00000033792, ENSCAFG00845020199, ENSG00000165240, ENSBTAG00000010018, ENSMMUG00000012871
|
| Target Classification |
Tumor-associated antigen (TAA)
|
ATP7A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo538 | Pre-made Human ATP7A/MK/MNK siRNA oligo Duplex | 538 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24941 | Pre-made Rat Atp7a/Mnk siRNA oligo Duplex | 24941 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11977 | Pre-made Mouse Atp7a/MNK siRNA oligo Duplex | 11977 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705857 | Pre-made Cynomolgus/Rhesus macaque ATP7A siRNA oligo Duplex | 705857 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086954 | Pre-made Cat/Feline ATP7A siRNA oligo Duplex | 101086954 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo406185 | Pre-made Dog/Canine ATP7A/MNK siRNA oligo Duplex | 406185 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541275 | Pre-made Bovines/Cattle ATP7A siRNA oligo Duplex | 541275 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071762 | Pre-made Equine/Horse ATP7A siRNA oligo Duplex | 100071762 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ATP7A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0116-Ab | Human | Anti-Human ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0116-Ab | Rat | Anti-Rat ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0116-Ab | Mouse | Anti-Mouse ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0116-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0116-Ab | Cat/Feline | Anti-Cat/Feline ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0116-Ab | Dog/Canine | Anti-Dog/Canine ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0116-Ab | Bovines/Cattle | Anti-Bovines/Cattle ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0116-Ab | Equine/Horse | Anti-Equine/Horse ATP7A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ATP7A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0116-Ag | Human | Human ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0116-Ag | Rat | Rat ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0116-Ag | Mouse | Mouse ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0116-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0116-Ag | Cat/Feline | Cat/Feline ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0116-Ag | Dog/Canine | Dog/Canine ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0116-Ag | Bovines/Cattle | Bovines/Cattle ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0116-Ag | Equine/Horse | Equine/Horse ATP7A VLP (virus-like particle) | HEK293 | Products Developing |
