Explore ASGR2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
| Target ID |
GM-MP0090
|
| Target Name |
ASGR2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
433
|
| Gene ID |
100687999 (Canis lupus familiaris), 11890 (Mus musculus), 29403 (Rattus norvegicus), 433 (Homo sapiens)
531519 (Bos taurus), 721779 (Macaca mulatta)
|
| Target Alternative Names |
ASGP-R 2,ASGP-R2,ASGPR 2,ASGPR2,ASGR2,Asgr,Asgr-2,Asgr2,Asialoglycoprotein receptor 2,C-type lectin domain family 4 member H2,CLEC4H2,HBXBP,HL-2,Hepatic lectin H2 (HL-2)
|
| Uniprot Accession |
P24721,P08290,P07307
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Thyroid hormone synthesis
|
| Gene Ensembl |
ENSMUSG00000040963, ENSG00000161944, ENSBTAG00000025101, ENSMMUG00000040495
|
ASGR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo433 | Pre-made Human ASGR2/HL-2/HBXBP siRNA oligo Duplex | 433 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29403 | Pre-made Rat Asgr2 siRNA oligo Duplex | 29403 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11890 | Pre-made Mouse Asgr2/Asgr/HL-2 siRNA oligo Duplex | 11890 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721779 | Pre-made Cynomolgus/Rhesus macaque ASGR2 siRNA oligo Duplex | 721779 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100687999 | Pre-made Dog/Canine ASGR2 siRNA oligo Duplex | 100687999 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo531519 | Pre-made Bovines/Cattle ASGR2 siRNA oligo Duplex | 531519 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
ASGR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0090-Ab | Human | Anti-Human ASGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0090-Ab | Rat | Anti-Rat ASGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0090-Ab | Mouse | Anti-Mouse ASGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0090-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ASGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0090-Ab | Dog/Canine | Anti-Dog/Canine ASGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0090-Ab | Bovines/Cattle | Anti-Bovines/Cattle ASGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ASGR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0090-Ag | Human | Human ASGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0090-Ag | Rat | Rat ASGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0090-Ag | Mouse | Mouse ASGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0090-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ASGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0090-Ag | Dog/Canine | Dog/Canine ASGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0090-Ag | Bovines/Cattle | Bovines/Cattle ASGR2 VLP (virus-like particle) | HEK293 | Products Developing |
