Explore Aquaporin 4/AQP4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Additional isoforms, resulting from the use of alternative in-frame translation initiation codons, have also been described. Recent studies provided evidence for translational readthrough in this gene, and expression of C-terminally extended isoforms via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]
| Target ID |
GM-MP0080
|
| Target Name |
Aquaporin 4/AQP4
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
361
|
| Gene ID |
100051905 (Equus caballus), 101081006 (Felis catus), 11829 (Mus musculus), 25293 (Rattus norvegicus) 281008 (Bos taurus), 361 (Homo sapiens), 612628 (Canis lupus familiaris), 703773 (Macaca mulatta)
|
| Target Alternative Names |
AQP-4,AQP4,Aqp4,Aquaporin 4,Aquaporin-4,MIWC,MLC4,Mercurial-insensitive water channel (MIWC),Miwc,WCH4,hAQP4
|
| Uniprot Accession |
P55088,P47863,O77750,P55087
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Diagnostics Biomarker
|
| Disease from KEGG |
Bile secretion
|
| Gene Ensembl |
ENSECAG00000004242, ENSMUSG00000024411, ENSBTAG00000051072, ENSG00000171885, ENSCAFG00845012372, ENSMMUG00000014934
|
Pre-made viral vector of Aquaporin 4/AQP4 cDNA Clones/ORF Plasmid
Aquaporin 4/AQP4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo361 | Pre-made Human AQP4/MIWC/MLC4 siRNA oligo Duplex | 361 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25293 | Pre-made Rat Aqp4/Miwc/WCH4 siRNA oligo Duplex | 25293 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11829 | Pre-made Mouse Aqp4/WCH4 siRNA oligo Duplex | 11829 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703773 | Pre-made Cynomolgus/Rhesus macaque AQP4 siRNA oligo Duplex | 703773 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081006 | Pre-made Cat/Feline AQP4 siRNA oligo Duplex | 101081006 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612628 | Pre-made Dog/Canine AQP4 siRNA oligo Duplex | 612628 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281008 | Pre-made Bovines/Cattle AQP4/MIWC/WCH4 siRNA oligo Duplex | 281008 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051905 | Pre-made Equine/Horse AQP4 siRNA oligo Duplex | 100051905 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Aquaporin 4/AQP4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0080-Ab | Human | Anti-Human Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-MP0080-Ab | Rat | Anti-Rat Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-MP0080-Ab | Mouse | Anti-Mouse Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-MP0080-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-MP0080-Ab | Cat/Feline | Anti-Cat/Feline Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-MP0080-Ab | Dog/Canine | Anti-Dog/Canine Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-MP0080-Ab | Bovines/Cattle | Anti-Bovines/Cattle Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-MP0080-Ab | Equine/Horse | Anti-Equine/Horse Aquaporin 4/AQP4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
Aquaporin 4/AQP4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0080-Ag | Human | Human Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0080-Ag | Rat | Rat Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0080-Ag | Mouse | Mouse Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0080-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0080-Ag | Cat/Feline | Cat/Feline Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0080-Ag | Dog/Canine | Dog/Canine Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0080-Ag | Bovines/Cattle | Bovines/Cattle Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0080-Ag | Equine/Horse | Equine/Horse Aquaporin 4/AQP4 VLP (virus-like particle) | HEK293 | Products Developing |