Explore AOC2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0071
|
| Target Name |
AOC2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
314
|
| Gene ID |
100336082 (Bos taurus), 100431015 (Macaca mulatta), 100630218 (Equus caballus), 101080592 (Felis catus)
237940 (Mus musculus), 314 (Homo sapiens), 490957 (Canis lupus familiaris)
|
| Target Alternative Names |
AOC2,Amine oxidase [copper-containing] 2,Amine oxidase copper-containing 2,Aoc2,DAO2,RAO,Retina-specific copper amine oxidase (RAO),SSAO,Semicarbazide-sensitive amine oxidase (SSAO)
|
| Uniprot Accession |
Q812C9,O75106
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSBTAG00000030334, ENSMMUG00000001870, ENSECAG00000011604, ENSMUSG00000078651, ENSG00000131480, ENSCAFG00845006922
|
Pre-made viral vector of AOC2 cDNA Clones/ORF Plasmid
AOC2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo314 | Pre-made Human AOC2/RAO/DAO2 siRNA oligo Duplex | 314 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo237940 | Pre-made Mouse Aoc2/RAO siRNA oligo Duplex | 237940 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100431015 | Pre-made Cynomolgus/Rhesus macaque AOC2 siRNA oligo Duplex | 100431015 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080592 | Pre-made Cat/Feline AOC2 siRNA oligo Duplex | 101080592 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490957 | Pre-made Dog/Canine AOC2 siRNA oligo Duplex | 490957 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336082 | Pre-made Bovines/Cattle AOC2 siRNA oligo Duplex | 100336082 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100630218 | Pre-made Equine/Horse AOC2 siRNA oligo Duplex | 100630218 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AOC2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0071-Ab | Human | Anti-Human AOC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0071-Ab | Mouse | Anti-Mouse AOC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0071-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AOC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0071-Ab | Cat/Feline | Anti-Cat/Feline AOC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0071-Ab | Dog/Canine | Anti-Dog/Canine AOC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0071-Ab | Bovines/Cattle | Anti-Bovines/Cattle AOC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0071-Ab | Equine/Horse | Anti-Equine/Horse AOC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
AOC2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0071-Ag | Human | Human AOC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0071-Ag | Mouse | Mouse AOC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0071-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AOC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0071-Ag | Cat/Feline | Cat/Feline AOC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0071-Ag | Dog/Canine | Dog/Canine AOC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0071-Ag | Bovines/Cattle | Bovines/Cattle AOC2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0071-Ag | Equine/Horse | Equine/Horse AOC2 VLP (virus-like particle) | HEK293 | Products Developing |
